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Publication Type : Journal Article
Publisher : Indian Journal of Cancer
Source : Indian Journal of Cancer, Volume 48, Number 4, p.471-476 (2011)
Keywords : adjuvant chemotherapy, adult, advanced cancer, aged, anaplastic carcinoma, article, cancer classification, cancer grading, cancer staging, Carcinoma, clear cell carcinoma, clinical assessment, clinical feature, disease association, Disease Progression, endometrium cancer, endometrium carcinoma, female, histopathology, human, Humans, hysterectomy, major clinical study, microscopy, middle aged, mucinous carcinoma, Neoplasm Staging, Ovarian Neoplasms, ovary cancer, predictive value, preoperative treatment, Retrospective Studies, retrospective study, serosa, Serous Membrane, tissue distribution, Uterine Neoplasms, uterus
Campus : Kochi
School : School of Medicine
Department : Gynecological Oncology
Year : 2011
Abstract : Context: Hysterectomy is an integral part of ovarian cancer surgery. The authors have evaluated the uterine involvement in ovarian cancer in this study. Aims: Conventionally, removal of the uterus is considered an essential part of ovarian cancer surgery, but rationale for same in absence of its gross involvement is questionable. Aim of this study was to evaluate the microscopic involvement of uterus in ovarian cancer and whether there are any predictors of uterine involvement. Settings and Design: Retrospective study. Materials and Methods: The authors analyzed 128 patients of epithelial ovarian cancer (EOC) operated from 2004 January to 2008 June, who had not undergone hysterectomy previously. Data regarding their demographic, clinical, and pathological findings was collected and analyzed. Statistical analysis used: Chi-square test. Results: Most of our patients (n=111) presented with stage III or above. Serous carcinoma was the most common histology encountered (86.7%). Uterus was grossly involved in only 19 patients and microscopic involvement was noted in 20 patients. Only one patient with absence of gross involvement had microscopic disease in the uterus. Involvement of the uterus was found to be independent of stage, type of tumor, laterality, and preoperative chemotherapy. The grade of tumor and gross uterine involvement were only factors that showed statistically significant correlation with microscopic uterine involvement. Only one patient had synchronous endometrial cancer. Conclusions: Uterine involvement in EOC is not common. Absence of gross uterine involvement reliably predicts absence of microscopic disease.
Cite this Research Publication : Ka Chitrathara, Sheikh, Z. Aa, Vijaykumar, D. Ka, Kuriakose, Sb, Anupama, Rb, and Nandeesh, Ma, “Is hysterectomy needed in ovarian cancer”, Indian Journal of Cancer, vol. 48, pp. 471-476, 2011.