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Lower urinary tract symptoms following neurological illness may be influenced by multiple factors: Observations from a neurorehabilitation service in a developing country

Publication Type : Journal Article

Thematic Areas : Medical Sciences

Publisher : Neurourology and Urodynamics

Source : Neurourology and Urodynamics, Volume 29, Number 3, p.378-381 (2010)

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Keywords : adult, arachnoiditis, arteriovenous malformation, article, bladder catheterization, bladder disease, brain damage, demyelination, Developing countries, developing country, disease association, echography, female, fluid intake, follow up, Guillain Barre syndrome, human, Humans, hydrocephalus, India, intervertebral disk hernia, lower urinary tract symptom, major clinical study, male, micturition disorder, muscarinic receptor blocking agent, myelitis, Nervous System Diseases, neurologic disease, neurologic examination, neuropathology, Parkinson disease, pathological anatomy, pons, Prospective Studies, prospective study, rehabilitation center, spine tumor, spondylosis, urinary dysfunction, urinary frequency, urinary hesitancy, Urination Disorders, urine incontinence, urine retention, urine volume

Campus : Kochi

School : School of Medicine

Department : Biostatistics

Year : 2010

Abstract : Aims: To evaluate the pattern of lower urinary tract dysfunction (LUTD) in patients with neurological disease in the setting of a rehabilitation service in a developing country, and analyze causes for unexpected lower urinary tract symptoms (LUTS). Methods: Patients with neurological disorders and having significant LUTS were prospectively evaluated. Level of neurological lesion was localized by neurological examination and investigations. LUTD was evaluated by symptom analysis, bladder diaries and ultrasonography. Storage symptoms were managed using antimuscarinic medications and voiding dysfunction, when significant, was managed by catheterization and patients were regularly followed up. Patients with symptoms that had not been expected based upon their level of neurological lesion were further evaluated. Results: Fifty patients (mean age 43.5 ± 18.3 years) were included and according to neurological localization, were categorized into suprapontine (n = 9; 18%), infrapontine/suprasacral (n = 25; 50%) or infrasacral (n = 16; 32%) groups. Incontinence was more common in patients with suprapontine and infrapontine/suprasacral lesions (n = 20) (P 0.03), hesitancy more common with infrapontine/suprasacral lesions (n = 20) (P = 0.004) and retention more with infrasacral lesions (n = 13) (P 0.001). Patients belonging to suprapontine and infrapontine/suprasacral groups more likely showed improvement at follow up (P = 0.008). Fourteen patients (28%) had unexpected LUTS and this was due to urological causes (n = 6) or multiaxial neurological involvement (n = 8). Potentially treatable factors were managed, resulting in symptom relief. Conclusion: LUTS in neurological disease may be at variance with the pattern expected based upon level of neurological lesion. Such patients may require further evaluation and consideration should be given to concomitant urological conditions and multiaxial neurological involvement. Neurourol. Urodynam. 29:378-381, 2010. Copyright © 2009 Wiley-Liss, Inc.

Cite this Research Publication : J. Nab Panicker, Menon, La, Anandkumar, Aa, Sundaram, K. Rc, and Fowler, C. Jb, “Lower urinary tract symptoms following neurological illness may be influenced by multiple factors: Observations from a neurorehabilitation service in a developing country”, Neurourology and Urodynamics, vol. 29, pp. 378-381, 2010.

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