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Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : ACS Applied Materials and Interfaces
Source : ACS Applied Materials and Interfaces, Volume 1, Number 11, p.2413-2419 (2009)
Keywords : Ag nanoparticle, Anti-Infective Agents, Antibacterial coatings, antiinfective agent, antimicrobial, Aspergillus niger, chemistry, Chlorine compounds, Composite materials, drug effect, Escherichia coli, Freestanding films, Glass substrates, Gram scale, letter, Loaded filter, metal nanoparticle, Metal Nanoparticles, methodology, methoxybenzyl chlorides, Microbial Sensitivity Tests, microbiological examination, Microorganisms, Nanocomposites, Nanoparticles, Nanotechnology, One pot, One-pot synthesis, Organic chemicals, organic compound, Organic solvents, Polycondensation, polymer, Polymer composite, Polymers, Reaction vessel, Room temperature, Silver, silver nanoparticles, solubility, spectrophotometry, Substrates, synthesis, Synthesis (chemical), ultrastructure, Ultraviolet, ultraviolet spectrophotometry
Campus : Kochi
School : School of Medicine
Department : Biostatistics
Year : 2009
Abstract : We report a one-pot synthesis of silver nanoparticle-polymer composites (Ag-PNCs) in water by a novel finding involving the polycondensation of methoxybenzyl chlorides (MeO-BzCl) directly on Ag nanoparticle surfaces at room temperature, leading to highly soluble antimicrobial nanocomposites. The composites, which are soluble in a range of organic solvents, precipitate in the reaction vessel, making their separation simple. Solutions of the composites can be casted directly on substrates or made into freestanding films. The material was found to be stable for nearly 2 years. A range of substrates have been shown to become antibacterial by direct application of this material. The experiments were conducted with Ag-PNC-loaded filter paper strips and glass substrates. The samples were found to be antimicrobial (against Escerichia coli and Aspergillus niger). The simple one-pot approach of this kind to make organic-soluble antibacterial coatings could have wide implications. © 2009 American Chemical Society.
Cite this Research Publication : A. S. Nair, Binoy, N. P., Ramakrishna, S., Kurup, T. R. R., Chan, L. W., Goh, C. H., Islam, M. R., Utschig, T., and Pradeep, T., “Organic-soluble antimicrobial silver nanoparticle-polymer composites in gram scale by one-pot synthesis”, ACS Applied Materials and Interfaces, vol. 1, pp. 2413-2419, 2009.