Publication Type : Journal Article
Publisher : International journal of medical and paediatric oncology.
Source : International journal of medical and paediatric oncology, Volume 37 (2016)
Keywords : Central nervous system tumors; childhood malignancies; neuroblastoma; positron emission tomography/computed tomography; sarcoma.
Campus : Kochi
School : School of Medicine
Department : Nuclear Medicine
Year : 2016
Abstract : (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) is a well-established imaging modality in adult oncological practice. Its role in childhood malignancies needs to be discussed as paediatric malignancies differ from adults in tumor subtypes and they have different tumor biology and FDG uptake patterns. This is also compounded by smaller body mass, dosimetric restrictions, and physiological factors that can affect the FDG uptake. It calls for careful planning of the PET study, preparing the child, the parents, and expertise of nuclear physicians in reporting pediatric positron emission tomography/computed tomography (PET/CT) studies. In a broad perspective, FDG-PET/CT has been used in staging, assessment of therapy response, identifying metastases and as a follow-up tool in a wide variety of pediatric malignancies. This review outlines the role of PET/CT in childhood malignancies other than hematological malignancies such as lymphoma and leukemia.
Cite this Research Publication : P. S, S, S. P., and A, T., “PET/CT in Paediatric Malignancies - An Update”, International journal of medical and paediatric oncology, vol. 37, 2016.