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Synthesis, Characterization, and Thermal Properties of Phosphorylated Chitin for Biomedical Applications

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Polymer Engineering & Science,

Source : Polymer Engineering & Science, Volume 49, Number 5, p.844-849 (2009)

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Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2009

Abstract : The present study investigates a suitable material, which is expected to have biocompatibility and to promote tissue regeneration. For this purpose, we have chosen chitin that was chemically modified by phosphorylation with high degree of substitution. The phosphorylated chitin (P-chitin) was synthesized using the H3PO4/P2O5/ET3PO4/hexanol method. The structure of P-chitin was analyzed by FTIR, 31P- and 13C-NMR spectroscopic studies, scanning electron microscopy, and X-ray diffraction. The thermal properties of the P-chitin were also characterized by thermogravimetric analyses. The highly phosphorylated chitin derivatives prepared by this method were soluble in water and amorphous in nature. Thus, H3PO4/P2O5/ET3PO4/hexanol method provides a versatile and alternative route for synthesis of P-chitin, which would be useful for biomedical applications. POLYM. ENG. SCI., 2009.

Cite this Research Publication : Dr. Jayakumar Rangasamy, Egawa, T., Furuike, T., Nair, S. V., and Tamura, H., “Synthesis, Characterization, and Thermal Properties of Phosphorylated Chitin for Biomedical Applications”, Polymer Engineering & Science, vol. 49, pp. 844-849, 2009.

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