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Publication Type : Journal Article
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : ACS Applied Materials and Interfaces
Source : ACS Applied Materials and Interfaces, American Chemical Society, Volume 10, Number 23, p.19449-19458 (2018)
Keywords : Biological properties, Cell attachments, Fabrication technique, Hydrophobic Material, Nanofibers, Protein adsorption, Robotic systems, Superhydrophilic behavior, Weaving, Woven products
Campus : Kochi
School : Center for Nanosciences
Center : Amrita Center for Nanosciences and Molecular Medicine Move
Department : Nanosciences and Molecular Medicine
Year : 2018
Abstract : This study investigates the unique properties, fabrication technique, and vascular applications of woven nanotextiles made from low-strength nanoyarns, which are bundles of thousands of nanofibers. An innovative robotic system was developed to meticulously interweave nanoyarns in longitudinal and transverse directions, resulting in a flexible, but strong woven product. This is the only technique for producing seamless nanotextiles in tubular form from nanofibers. The porosity and the mechanical properties of nanotextiles could be substantially tuned by altering the number of nanoyarns per unit area. Investigations of the physical and biological properties of the woven nanotextile revealed remarkable and fundamental differences from its nonwoven nanofibrous form and conventional textiles. This enhancement in the material property was attributed to the multitude of hierarchically arranged nanofibers in the woven nanotextiles. This patterned woven nanotextile architecture leads to a superhydrophilic behavior in an otherwise hydrophobic material, which in turn contributed to enhanced protein adsorption and consequent cell attachment and spreading. Short-term in vivo testing was performed, which proved that the nanotextile conduit was robust, suturable, kink proof, and nonthrombogenic and could act as an efficient embolizer when deployed into an artery. © 2018 American Chemical Society.
Cite this Research Publication : J. Joseph, Krishnan, A. G., Cherian, A. M., Rajagopalan, B., Jose, R., Dr. Praveen Varma, Maniyal, V., Balakrishnan, S., Shantikumar V Nair, and Dr. Deepthy Menon, “Transforming Nanofibers into Woven Nanotextiles for Vascular Application”, ACS Applied Materials and Interfaces, vol. 10, pp. 19449-19458, 2018.