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Treatment planning and dosimetric comparison study on two different volumetric modulated arc therapy delivery techniques

Publication Type : Journal Article

Thematic Areas : Medical Sciences

Publisher : Reports of Practical Oncology and Radiotherapy

Source : Reports of Practical Oncology and Radiotherapy, Volume 18, Number 2, p.87-94 (2013)

Url : is external)

Keywords : article, bladder, clinical article, dosimetry, esophagus, female, human, lung, male, mandible, parotid gland, radiation dose distribution, Radiotherapy, rectum, treatment planning, uterine cervix, volumetric modulated arc therapy

Campus : Kochi

School : School of Medicine

Center : Amrita Institute of Medical Science

Department : General Medicine

Verified : Yes

Year : 2013

Abstract : Aim: To compare and evaluate the performance of two different volumetric modulated arc therapy delivery techniques. Background: Volumetric modulated arc therapy is a novel technique that has recently been made available for clinical use. Planning and dosimetric comparison study was done for Elekta VMAT and Varian RapidArc for different treatment sites. Materials and methods: Ten patients were selected for the planning comparison study. This includes 2 head and neck, 2 oesophagus, 1 bladder, 3 cervix and 2 rectum cases. Total dose of 50. Gy was given for all the plans. All plans were done for RapidArc using Eclipse and for Elekta VMAT with Monaco treatment planning system. All plans were generated with 6. MV X-rays for both RapidArc and Elekta VMAT. Plans were evaluated based on the ability to meet the dose volume histogram, dose homogeneity index, radiation conformity index, estimated radiation delivery time, integral dose and monitor units needed to deliver the prescribed dose. Results: RapidArc plans achieved the best conformity (CI95%=1.08±0.07) while Elekta VMAT plans were slightly inferior (CI95%=1.10±0.05). The in-homogeneity in the PTV was highest with Elekta VMAT with HI equal to 0.12±0.02Gy when compared to RapidArc with 0.08±0.03. Significant changes were observed between the RapidArc and Elekta VMAT plans in terms of the healthy tissue mean dose and integral dose. Elekta VMAT plans show a reduction in the healthy tissue mean dose (6.92±2.90)Gy when compared to RapidArc (7.83±3.31)Gy. The integral dose is found to be inferior with Elekta VMAT (11.50±6.49)×104Gycm3 when compared to RapidArc (13.11±7.52)×104Gycm3. Both Varian RapidArc and Elekta VMAT respected the planning objective for all organs at risk. Gamma analysis result for the pre-treatment quality assurance shows good agreement between the planned and delivered fluence for 3mm DTA, 3% DD for all the evaluated points inside the PTV, for both VMAT and RapidArc techniques. Conclusion: The study concludes that a variable gantry speed with variable dose rate is important for efficient arc therapy delivery. RapidArc presents a slight improvement in the OAR sparing with better target coverage when compared to Elekta VMAT. Trivial differences were noted in all the plans for organ at risk but the two techniques provided satisfactory conformal avoidance and conformation. © 2012 Greater Poland Cancer Centre.

Cite this Research Publication : S. AaSyam Kumar, Holla, Rb, Sukumar, Pa, Padmanaban, Sa, and Vivekanandan, Na, “Treatment planning and dosimetric comparison study on two different volumetric modulated arc therapy delivery techniques”, Reports of Practical Oncology and Radiotherapy, vol. 18, pp. 87-94, 2013.

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