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Warfarin Resistance Mechanism & Management

Publication Type : Journal Article

Publisher : IJPSR

Source : International Journal of Pharmaceutical Sciences & Research (IJPSR), Volume 3, Number 2 (2012)

Url :

Campus : Kochi

School : School of Pharmacy

Department : Pharmacy Practice

Year : 2012

Abstract : Anticoagulants are a class of drugs commonly used to prevent the blood from forming dangerous clots that could result in a stroke.Warfarin is an oral anticoagulant. Warfarin differs from most other drugs in that the dosage required to achieve a desired therapeutic effect varies greatly among individuals. Resistance to warfarin has been described as the inability to prolong the prothrombin time or raise the international normalized ratio (INR) into the therapeutic range when the drug is given at normally prescribed doses. However, a higher warfarin requirement does not itself establish the diagnosis of warfarin resistance. Warfarin resistance can be classified as acquired versus hereditary. It can be diagnosed by laboratory studies and can be managed.

Cite this Research Publication : L. R, Roshni P. R., and S., A., “Warfarin Resistance Mechanism & Management”, International Journal of Pharmaceutical Sciences & Research (IJPSR), vol. 3, 2012.

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