Course

Unit I

Drugs and Pharmaceuticals (14 hours)Drug discovery, design and development; Basic Retrosynthetic approach. Synthesis of the representative drugs of the following classes: analgesics agents, antipyretic agents, anti-inflammatory agents (Aspirin, paracetamol, lbuprofen); antibiotics (Chloramphenicol); antibacterial and antifungal agents (Sulphonamides; Sulphanethoxazol, Sulphacetamide, Trimethoprim); antiviral agents (Acyclovir), Central Nervous System agents (Phenobarbital, Diazepam),Cardiovascular (Glyceryl trinitrate), antilaprosy (Dapsone), HIV-AIDS related drugs (AZT- Zidovudine).

Unit II

Cosmetics and Perfumes (11 hours)A general study including preparation and uses of the following: Hair dye, hair spray, Shampoo, Sun-tan lotions, face powder, lipsticks, talcum powder, nail enamel, creams (cold, vanishing and shaving creams), antiperspirants and artificial flavours. Essential oils and their importance in cosmetic industries with reference to Eugenol, Geraniol, sandalwood oil, eucalyptus, rose oil, ?-phenyl ethyl alcohol, Jasmone, Civetone, Muscone.

TEXTBOOKS / REFERENCES:1) E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.2) P.C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.3) B.K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.4) G.L. Patrick: Introduction to Medicinal Chemistry, Oxford University Press, UK.5) Hakishan, V.K. Kapoor: Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, Pitampura, New Delhi.6) R. Cremlyn: Pesticides, John Wiley.7) William O. Foye, Thomas L., Lemke , David A. William: Principles of Medicinal Chemistry, B.I. Waverly Pvt Ltd. New Delhi.