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Course Detail

Course Name Developmental Biology
Program BSc. in Biotechnology
Semester Six
Credits Three
Year Taught 2019


History & Basic concepts of development
  • Overview of how the modern era of developmental biology emerged through multidisciplinary approaches
  • stages of development- zygote, blastula, gastrula ,neurula
  • cell fate & commitment –  potency- concept of embryonic stem cells,  differential gene expression, terminal differentiation ,lineages of three germ layers, fate map
  • Mechanisms of differentiation-  cytoplasmic determinants, embryonic induction,  concept of morphogen,  mosaic and regulative development
  • Pattern formation–   axis specification,   positional identification (regional specification)
  • Morphogenetic movements
  • Model organisms    in Developmental biology
2. Early Development in invertebrate /vertebrate models
  • Drosophila, C.elegans,   Xenopus,  Mouse/ human
  • Cleavage, gastrulation, Axis specification (Dorsoventral, anterior posterior), & body plan patterning,   left right asymmetry in vertebrates
3. Late Development in invertebrate /vertebrate models

Organogenesis- development of central nervous system in vertebrates,  vulval formation in C.elegans

4. Germ cell specification& migration
5. Overview of plant development
6. Medical implications of developmental biology - genetic errors/ teratogenesis/ stem cell therapy etc
Syllabus - Year Taught
2015 2014

Text Books


Website:   virtual embryo

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