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Course Detail

Course Name Introduction to Translational Medicine    
Course Code 24TM501
Program M.Sc. in Translational Medicine
Semester I
Credits 3
Campus Faridabad

Syllabus

Syllabus

Unit 1:
Introduction to Translational Medicine; Definition and significance, Historical perspective.
Unit 2:
Bench to Bedside: The Translational Continuum; Basic research, Preclinical studies, Clinical trials, Implementation in clinical practice.
Unit 3:
Methodologies in Translational Medicine, Biomarker discovery and validation, Omics technologies (Genomics, Proteomics, Metabolomics), Imaging techniques, Computational modeling and simulation
Unit 4:
Challenges in Translational Research, Regulatory hurdles, Intellectual property issues,
Unit 5:
Interdisciplinary Collaboration in Translational Medicine, Team science approach, Collaboration between academia, industry, and healthcare institutions.
Unit 6:
Ethical Considerations in Translational Medicine; Informed consent, Data privacy and confidentiality, Equity and access to healthcare innovations
Unit 7:
Current Trends and Future Directions; Precision medicine, Personalized therapies, Data-driven approaches, Global health implications.

Objectives and Outcomes

Preamble

Introduction to Translational Medicine is a graduate-level course designed to provide students with a comprehensive understanding of the principles, methodologies, and applications of translational medicine. Translational medicine bridges the gap between basic research findings and clinical applications, aiming to improve patient care and outcomes. This course will cover various aspects of translational medicine, including the process of translating scientific discoveries into clinical practice, the role of interdisciplinary collaboration, ethical considerations, and current trends in the field.

Course outcome

CO1: To understand the concept and significance of translational medicine.
CO2: To explore the continuum from basic research to clinical applications.
CO3: To examine the methodologies and approaches used in translational medicine.
CO4: To analyze the challenges and opportunities in translating scientific discoveries into clinical practice.
CO5: To discuss the role of interdisciplinary collaboration in translational research.
CO6: To evaluate ethical, regulatory and quality standard considerations in translational medicine.
CO7: To review current trends and advancements in the field of translational medicine.

Program outcome (PO)

PO1: Utilize scientific principles and methodologies to design innovative solutions for data analysis, experimentation, and product development for challenges in translational research.
PO2: Recognize the importance of environmental sustainability in translational research and strive to minimize adverse environmental impacts.
PO3: Engage in ethical conduct, leadership, active listening, constructive feedback, and interpersonal communication to facilitate productive collaborations and knowledge exchange.
PO4: Acquire fundamental and advanced knowledge and skills in project management, financial planning, and entrepreneurship relevant to translational research ventures and initiatives.
3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity

CO – PO Mapping

PO1 PO2 PO3 PO4
CO 1 1 1 1 3
CO 2 2 1 2 3
CO 3 3 1 1 2
CO 4 3 1 1 2
CO 5 1 1 3 1
CO6 1 3 1 2
CO7 1 1 1 3

Program Specific Outcome (PSO)

PSO1: Addresses the complexity of interdisciplinary sciences in biological and medical contexts.

PSO2: Deals with regulatory affairs in medicine, covering topics such as ethical considerations and regulatory frameworks.

PSO3: Covers compounds as drugs and their efficacy, involving pharmacology and drug development.

PSO4: Explores the intersection of bioinformatics and artificial intelligence in biology and medicine.

PSO5: Deals with technology in personalizing medicine, involving precision medicine approaches.

PSO6: Focuses on communicating and disseminating science and medicine to the public, involving science communication and public outreach efforts.

PSO1 PSO2 PSO3 PSO4 PSO5 PSO6
CO 1 1 2 3
CO 2 2 2 2 2
CO 3 3 3 3 3
CO 4 3 1
CO 5 1 2 2 1 3
CO6 1 3 1 2
CO7 1 3 1 3

Textbooks

Alberts, B., 2017. Molecular biology of the cell. (5th Edition) Garland science.
Machin, D., Day, S. and Green, S. eds., 2007. Textbook of clinical trials. John Wiley & Sons.

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