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Course Detail

Course Name Pharmaceutical Organic Chemistry – Practical
Program Pharm. D.
Semester One & Two
Year Taught 2014 , 2015 , 2016 , 2017 , 2018


‘Pharmaceutical Organic Chemistry – Practical’ is a course offered in the first year of Pharm. D. program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.


Course Duration: 3 Hrs./Week

Lecture Wise Program

List of Experiments:

  1. Introduction to the various laboratory techniques through demonstration involving synthesis of the following compounds (at least 8 compounds to be synthesised):
    1. Acetanilde / aspirin (Acetylation)
    2. Benzanilide / Phenyl benzoate (Benzoylation)
    3. P-bromo acetanilide / 2,4,6 – tribromo aniline (Bromination)
    4. Dibenzylidene acetone (Condensation)
    5. 1-Phenylazo-2-napthol (Diazotisation and coupling)
    6. Benzoic acid / salicylic acid (Hydrolysis of ester)
    7. M-dinitro benzene (Nitration)
    8. 9, 10 – Antharaquinone (Oxidation of anthracene) / preparation of benzoic acid from toluene or benz- aldehyde
    9. M-phenylene diamine (Reduction of M-dinitrobenzene) / Aniline from nitrobenzene
    10. Benzophenone oxime
    11. Nitration of salicylic acid
    12. Preparation of picric acid
    13. Preparation of O-chlorobenzoic acid from O-chlorotolune
    14. Preparation of cyclohexanone from cyclohexanol
  2. Identification of organic compounds belonging to the following classes by :
    Systematic qualitative organic analysis including preparation of derivatives Phenols, amides, carbo- hydrates, amines, carboxylic acids, aldehyde and ketones, Alcohols, esters, hydrocarbons, anilides, nitrocompounds.
  3. Introduction to the use of stereo models:
    Methane, Ethane, Ethylene, Acetylene, Cis alkene, Trans alkene, inversion of configuration.

Scheme of Practical Examination:

  Sessionals Annual
Synopsis 05 15
Major Experiment 10 25
Minor Experiment 03 15
Viva 02 15
Max Marks 20 70
Duration 03 hrs 04 hrs

Note : Total sessional marks is 30 (20 for practical sessional plus 10 marks for regularity, promptness, viva-voce and record maintenance).

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