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Dr. Renuka Suravajhala

Research Scientist, School of Biotechnology, Amritapuri

Qualification: Ph.D
renus@am.amrita.edu
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Research Interest: Cancer Biology, Lead Discovery, Structural and Synthetic Biology

Bio

Dr. Renuka Suravajhala is a Ph.D in Synthetic Biology from Manipal University, India. Her interests are in lieu of the synthesis of nano-polymers, their analytical validation and application in selective targeted drug delivery systems. Renuka obtained her B.Sc. in Chemistry (Honors) and M.Sc. in Organic Chemistry, both from Kakatiya University, India. She was a recipient of the JNCASR fellowship in 2001 as part of her Master’s program and later received the Ramdas Pai award for excellence in research. She has worked in the Department of Chemical Engineering, Indian Institute of Science (IISc) Bangalore and later at the Indian Institute of Chemical Technology, Hyderabad besides working for Roskilde University, Denmark where she focused on the methylation mechanisms in breast and colon cancers. She also honed skills as a clinical data manager and medical writer at the James Lind Institute, Singapore. Over the last 10 years, she has led focus on structural biology of human diseases where she has been instrumental in identifying successful lead molecules. She has published over 20 research papers in peer reviewed journals and also participated in various national and international conferences. She is also a founder of Women in Biology forum of Bioclues.org, where she has been leading women empowerment for career rebuilding (WE-CARE) programme since 2009.

Publications

Journal Article

Year : 2021

Molecular docking and dynamics studies of curcumin with COVID-19 proteins

Cite this Research Publication : Suravajhala, R.; Parashar, A.; Choudhir, G.; Kumar, A.; Malik, B.; Nagaraj, V. A.; Padmanaban, G.; Polavarapu, R.; Suravajhala, P.; Kishor, P. B. K. Molecular Docking and Dynamics Studies of Curcumin with COVID-19 Proteins. Netw Model Anal Health Inform Bioinforma 2021, 10 (1), 44. https://doi.org/10.1007/s13721-021-00312-8.

Publisher : Netw Model Anal Health Inform Bioinforma

Year : 2021

Selective Recognition of Caffeine by (3-aminopropyl) Triethoxysilane Based Polymers

Cite this Research Publication : Suravajhala, R.; Malik, B. Selective Recognition of Caffeine by (3-Aminopropyl) Triethoxysilane Based Polymers. CNANO 2021, 17. https://doi.org/10.2174/1573413717666210809105214.

Publisher : CNANO

Year : 2021

Development of Highly Specific and Selectively Recognizing Caffeine Imprinted Polymer Nanomaterials with EGDMA Crosslinker

Cite this Research Publication : Suravajhala, R.; Burri, H. R.; Malik, B. Development of Highly Specific and Selectively Recognizing Caffeine Imprinted Polymer Nanomaterials with EGDMACrosslinker. CNM,2021, 06. https://doi.org/10.2174/2405461506666210603121936.

Publisher : CNM

Year : 2021

The Omic Insights on Unfolding Saga of COVID-19

Cite this Research Publication : Kaur A, Chopra M, Bhushan M, Gupta S, Kumari P H, Sivagurunathan N, Shukla N, Rajagopal S, Bhalothia P, Sharma P, Naravula J, Suravajhala R, Gupta A, Abbasi BA, Goswami P, Singh H,
Narang R, Polavarapu R, Medicherla KM, Valadi J, Kumar S A, Chaubey G, Singh KK, Bandapalli OR, Kavi Kishor PB, Suravajhala P. The Omic Insights on Unfolding Saga of COVID-19. Front Immunol. 2021 Oct 20;12:724914. doi: 10.3389/fimmu.2021.724914. PMID: 34745097; PMCID: PMC8564481

Publisher : Front Immunol

Year : 2021

SARS-CoV-2 transgressing LncRNAs uncovers the known unknowns

Cite this Research Publication : Shukla N, Prasad A, Kanga U, Suravajhala R, Nigam VK, Kishor PBK, Polavarapu R, Chaubey G, Singh KK, Suravajhala P. SARS-CoV-2 transgressing LncRNAs uncovers the known unknowns. Physiol Genomics. 2021 Oct 1;53(10):433-440. doi: 10.1152/physiolgenomics.00075.2021. Epub 2021 Sep 7. PMID: 34492207; PMCID: PMC8562947

Publisher : Physiol Genomics. 2021 Oct 1;53(10):433-440

Year : 2020

Emerging Toxicity Aspects of Silver Nanoparticles: An Overview

Cite this Research Publication : Suravajhala, R.; Bhagat, M.; Malik, B. Emerging Toxicity Aspects of Silver Nanoparticles: An Overview. CNANOM 2020, 10. https://doi.org/10.2174/2468187310999200712184531.

Publisher : CNANOM

Year : 2020

Cedrus deodara (Bark) Essential Oil Induces Apoptosis in Human Colon Cancer Cells by Inhibiting Nuclear Factor kappa B

Cite this Research Publication : Bhagat, M.; Kumar, A.; Suravajhala, R. Cedrus Deodara (Bark) Essential Oil Induces Apoptosis in Human Colon Cancer Cells by Inhibiting Nuclear Factor Kappa B. CTMC 2020, 20 (22), 1981–1992. https://doi.org/10.2174/1568026620666200722120826.

Publisher : CTMC

Year : 2020

Selective Targeted Drug Delivery Mechanism via Molecular Imprinted Polymers in Cancer Therapeutics

Cite this Research Publication : Suravajhala, R.; Burri, H. R.; Malik, B. Selective Targeted Drug Delivery Mechanism via Molecular Imprinted Polymers in Cancer Therapeutics. CTMC 2020, 20 (22), 1993–1998. https://doi.org/10.2174/1568026620666200622150710.

Publisher : CTMC

Year : 2020

Lysine, Lysine-Rich, Serine, and Serine-Rich Proteins: Link Between Metabolism, Development, and Abiotic Stress Tolerance and the Role of ncRNAs in Their Regulation

Cite this Research Publication : Kishor, P. B. K.; Suravajhala, R.; Rajasheker, G.; Marka, N.; Shridhar, K. K.; Dhulala, D.; Scinthia, K. P.; Divya, K.; Doma, M.; Edupuganti, S.; Suravajhala, P.; Polavarapu, R. Lysine, Lysine-Rich, Serine, and Serine-Rich Proteins: Link Between Metabolism, Development, and Abiotic Stress Tolerance and the Role of NcRNAs in Their Regulation. Front. Plant Sci. 2020, 11, 546213. https://doi.org/10.3389/fpls.2020.546213.

Publisher : Front. Plant Sci.

Year : 2020

Bioactive Potential of Cedrus Deodara (Roxb.) Loud Essential Oil (Bark) against Curvularia Lunata and Molecular Docking Studies.

Cite this Research Publication : Kumar, A.; Suravajhala, R.; Bhagat, M. Bioactive Potential of Cedrus Deodara (Roxb.) Loud Essential Oil (Bark) against Curvularia Lunata and Molecular Docking Studies. SN Appl. Sci. 2020, 2 (6), 1045. https://doi.org/10.1007/s42452-020-2837-6.

Publisher : . SN Appl. Sci.

Year : 2019

A Molecular Docking and Pharmacokinetic Prediction of Thiazolidine-2, 4-dione Derivatives: Toward Novel Therapeutic Targets for Type-2 Diabetes Mellitus

Cite this Research Publication : Tiwari, P.; Suravajhala, R.; Gupta, S.; Chaturvedi, P.; Mathur, S. K.; Solanki, P. S.; Malik,B. A Molecular Docking and Pharmacokinetic Prediction of Thiazolidine-2, 4-Dione Derivatives: Toward Novel Therapeutic Targets for Type-2 Diabetes Mellitus. International. Journal for Computational Biology (IJCB) 2019, 8 (1).

Publisher : IJCB

Year : 2014

STUDIES ON 8-TERTBUTYL CAFFEINE: AN IN SILICO APPROACH TO MECHANISTIC STUDIES

Cite this Research Publication : Suravajhala, R.; Varadwaj, P. K. STUDIES ON 8-TERTBUTYL CAFFEINE: AN IN SILICO APPROACH TO MECHANISTIC STUDIES. International Journal for Computational Biology 2014, 2 (1), 12. https://doi.org/10.34040/IJCB.2.1.2014.12.

Publisher : International Journal for Computational Biology

Year : 2014

The Making of the Women in Biology Forum (WiB) at Bioclues

Cite this Research Publication : Singhania, R. R.; Madduru, D.; Pappu, P.; Panchangam, S.; Suravajhala, R.; Chandrasekharan, M. The Making of the Women in Biology Forum (WiB) at Bioclues. PLoS Comput Biol 2014, 10 (1), e1003436. https://doi.org/10.1371/journal.pcbi.1003436.

Publisher : PLoS Comput Biol

Year : 2013

Biological evaluation of 8-alkyl xanthines as potential cytotoxic agents

Cite this Research Publication : Suravajhala, R.; Suri, N.; Bhagat, M.; Saxena, A. K. Biological Evaluation of 8-Alkyl Xanthines as Potential Cytotoxic Agents. ABC 2013, 03 (03), 314–319. https://doi.org/10.4236/abc.2013.33035.

Publisher : ABC

Year : 2013

Synthesis of C-8 Alkyl Xanthines by Pentaamminecobalt(III) Complex.

Cite this Research Publication : Suravajhala, R. Synthesis of C-8 Alkyl Xanthines by Pentaamminecobalt(III) Complex. ABC 2013, 03 (06), 521–524. https://doi.org/10.4236/abc.2013.36058.

Publisher : ABC

Book Chapter

Year : 2022

Omics in medicinal plants

Cite this Research Publication : Shalini Mukherjee.;P. HimaKumari.; Surendra Satyanarayan Agrawal.; Saraswathy Nagendran.; RenukaSuravajhala, Omics in medicinal plants, Omics in Horticultural Crops,2022. https://doi.org/10.​1016/​B978-0-323-89905-5.​00007-0.

Publisher : Omics in Horticultural Crops

Year : 2020

Biomimetic Approaches in Synthetic Biology

Cite this Research Publication : Suravajhala, R.; Kumar, A.; Burri, H. R.; Malik, B. Biomimetic Approaches in Synthetic Biology. In Advances in Synthetic Biology; Singh, V., Ed.; Springer: Singapore, 2020; pp 81– 97. https://doi.org/10.1007/978-981-15-0081-7_6.

Publisher : Springer: Singapore

Year : 2020

Recent Advances in Gene and Genome Assembly: Challenges and Implications

Cite this Research Publication : Agarwal, T.; Suravajhala, R.; Bhushan, M.; Goswami, P.; Iddamalgoda, L.; Malik, B.; Valadi, J.; Suravajhala, P. Recent Advances in Gene and Genome Assembly: Challenges and Implications. In Advances in Synthetic Biology; Singh, V., Ed.; Springer Singapore: Singapore, 2020; pp 199–220. https://doi.org/10.1007/978-981-15-0081-7_12.

Publisher : Springer Singapore

Awards and Recognitions

Best Poster award,National Science dayRamdas Pai Fellowship, Manipal University Jaipur, (February 2020)
Ramdas Pai Fellowship, Manipal University Jaipur, (June 2018)
JNCASR fellowship, JNCASR, Bengaluru, Government of India, 2002.

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