Back close

Seabuckthorn – A Repository of Bioactive Phytochemicals

Start Date: Thursday, Jan 01,2009

School: School of Biotechnology

Project Incharge:Dr. Bipin Kumar G. Nair
Funded by:DBT
Seabuckthorn – A Repository of Bioactive Phytochemicals

Seabuckthorn (SBT), (Hippophae L.) are deciduous shrubs in the genus Hippophae, family Elaeagnaceae. In addition to the nutritionally active constituents, many clinically important activities of seabuckthorn (SBT), such as beneficial effects on skin, cardiovascular diseases, diabetes, wound healing, cancer chemopreventive action, antiviral activity, sun screen and radioprotection have been established. Unfortunately, most of the reported studies have been carried out with ill-defined crude extracts (e g “flavone”, “hydro alcoholic extracts”, “SBT oil”, “aqueous extracts”). 

Due to non-uniformity, the results are often not reproducible. Therefore there is urgent need for identification of active principles. Presently, work in the laboratory is directed towards the isolation and characterization of active principles/fractions from bioactive fractions of SBT. Isolated compounds will be available for the treatment of diseases such as diabetes, dermatitis, CVD, peptic ulcers, sun-screen and radio protective formulations, wound healing agents. Wherever isolation presents difficulty within a reasonable time frame, the extracts will be standardized with respect to bio-markers and fingerprinting.

Publications:

  1. “Drug Discovery Through Seabuckthorn Research,” Chinchu Bose and A. Banerji, invited presentation at the Fourth International Seabuckthorn Association Conference (ISA 2009): Seabuckthorn on the way between Science and Industry Interaction, Belokuriha, Russia, September2009
  2. “Synthesis and Antioxygenic Properties of Seabuckthorn Flavones-3-ols and Analogs”,N. Pandurangan, Chinchu Bose, and A. Banerji, Bioorganic & Medicinal Chemistry Letters21 (2011) 5328– 5330

Related Projects

Studies on the Use of Bacterial Cell as Glucose Biosensor
Studies on the Use of Bacterial Cell as Glucose Biosensor
Development of peptide inhibitors against functional components of snake venom; a new approach
Development of peptide inhibitors against functional components of snake venom; a new approach
Antimicrobial Activity of Selected Plant Extracts on Multi Drug Resistant Staphylococcus Aureus
Antimicrobial Activity of Selected Plant Extracts on Multi Drug Resistant Staphylococcus Aureus
Green synthesis of Metal Nano Particles like Gold or Silver and its Application
Green synthesis of Metal Nano Particles like Gold or Silver and its Application
Value addition to seabukthorn through isolation & characterisation of pharmacologically active compounds
Value addition to seabukthorn through isolation & characterisation of pharmacologically active compounds
Admissions Apply Now