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Publication Type : Journal Article
Publisher : IJPSRR
Source : IJPSRR, Volume 2 (2011)
Campus : Kochi
School : School of Pharmacy
Department : Pharmaceutical Chemistry & Analysis
Year : 2011
Abstract : The aim of the present study was to determine lipid lowering property of ethanol extract of Vitex negundo linn.The phytochemical studies performed as described by Wagner et al. Acute toxicity studies were performed initially in order to determine the safety of ethanol extract of Vitex negundo linn. (EEVN). In the present study the ethanol extract of Vitex negundo L. results a significant dose dependent reduction in Total Cholesterol and Low Density Lipoprotein level when compared with Cholesterol control group. Also all the treatment groups show a little bit increase in HDL level. Up on the triglycerides level the extracts posses a significant activity when com-pared to Lovastatin treated groups. The results demonstrate the effectiveness of the leaf of Vitex negundo L. as an anti-atherogenic agent preventing coronary artery diseases.
Cite this Research Publication : E. Githa, Mathew,, and Bijo Mathew, “Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats”, IJPSRR, vol. 2, 2011.