Publication Type : Conference Proceedings
Thematic Areas : Biotech
Publisher : Springer
Source : Proceedings of the Indian Academy of Sciences-Chemical Sciences, Springer, Volume 106, p.1149-1156 (1994)
Url : http://link.springer.com/article/10.1007%2FBF02841922
Campus : Amritapuri
School : School of Biotechnology
Center : Biotechnology, Phytochemistry Labs
Department : biotechnology, Chemistry
Year : 1994
Abstract : During a search for bioactive compounds from indigenous plants,Pimpinella monoica (Umbelliferae) was found to contain furocoumarin, isopimpenellin (3) and five biogenetically related furocoumarins viz khellin (1), visnagin (2), visamminol (4), ammiol (5) and khellol (6). Labelled (i) and (2) were isolated from [1−14C]- and [2−14C]-acetates. Labelling pattern, determined by degradation of biosynthesised compounds, establishes the polyketide origin of their aromatic and pyrone rings while the furan ring originates via an acetate-mevalonate pathway. The plant also utilises glycine and leucine as substratevia acetate. Biotransformation of [3−3H]-visnagin to (6) but not to (2) was also observed.
Cite this Research Publication : D. L. Luthria and Banerji, A., “Biosynthesis of furanochromones inPimpinella monoica”, Proceedings of the Indian Academy of Sciences-Chemical Sciences, vol. 106. Springer, pp. 1149-1156 , 1994.