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CD45 Tyrosine Phosphatase Inhibitory Components from Aspergillus niger

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : J. Antibiotics

Source : J. Antibiotics, Issue 53, p.110-113 (2000)

Campus : Amritapuri

School : School of Biotechnology

Center : Cell Biology

Department : biotechnology, Microbiology

Year : 2000

Abstract : Two inhibitors of CD45 tyrosine phosphatase, dihydrocarolic acid (1) and penitricin D (2), were isolated from a fermentation broth of the fungus Aspergillus niger and purified by HSCCC (high speed countercurrent chromatography) followed by HPLC. The structures were determined by NMR. The inhibitory activities of both compounds were specific to tyrosine phosphatases.

Cite this Research Publication : K. A. Alvi, Dr. Bipin G. Nair, J. Rabenstein, G. Davis, and D. B. Baker, “CD45 Tyrosine Phosphatase Inhibitory Components from Aspergillus niger”, J. Antibiotics, no. 53, pp. 110-113, 2000

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