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Characterization of powder metallurgy processed magnesium alloys for biomedical implants

Publication Type : Journal Article

Source : Emergent Materials, 2023

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Keywords : Magnesium alloys, Powder metallurgy, Hardness, In vitro cytotoxicity, Biomedical, Implants

Campus : Coimbatore

School : School of Engineering

Department : Mechanical Engineering

Verified : No

Year : 2023

Abstract : Magnesium (Mg) and its alloys, with their mechanical behavior, biodegradable material with unique antibacterial features, and nontoxicity, find potential application in the field of Biomedical nevertheless, its high level of reactivity limits its usage. One promising way to enhance mechanical behavior is to fabricate Mg-based alloy using the powder metallurgy (PM) technique. The corrosion resistance of these alloys is influenced owing to the introduced plastic deformation. In this work, three pure Mg samples (Mg-Al-Zr-Mn, Mg-Nd-Zr, Mg-Nd-Zn-Zr) were fabricated using the PM technique applying a pressure of 2 MPa for compacting. All the fabricated samples were tested for their density, and it was noted that Mg-Al-Zr-Mn and Mg-Nd-Zr possess the lowest density. XRD analysis was conducted on all PM samples to determine the intermediate phases present in the fabricated samples. Furthermore, the compacted samples were subjected to a Vickers microhardness, corrosion test, and in vitro cytotoxicity. The Mg-Nd-Zn-Zr alloy showed 20.77% more microhardness than the Mg-Al-Zr-Mn alloy. The electrochemical corrosion characteristic of the fabricated PM samples was analyzed using the electrochemical impedance spectroscopy carried out in Ringer's solution and was linked with the microstructural analysis of the corrosion process. The samples' corrosion potential, current, and rate were determined from this test, and it was observed that the Mg-Nd-Zr-Zn showed a minimum corrosion rate. Upon studying the cytotoxicity test, it was evaluated that the Mg-Nd-Zn-Zr alloy exhibited cytotoxicity of 0% and cell viability more significant than 99%. Among the researched PM samples, Mg-Nd-Zn-Zr showed better properties and hence can be recommended for the manufacturing of implants for biomedical applications.

Cite this Research Publication : Balan, P (Balan, Pranesh) ; Thiagarajan, V (Thiagarajan, Velmurugan) ; Ganesan, SP (Ganesan, Suganya Priyadharshini) ; Raghunathan, V (Raghunathan, Vishnu) ; Shankar, KV (Shankar, Karthik Venkitraman) ; Kumar, BGY (Kumar, B. G. Yashwanth) ; Ramalingam, VV (Ramalingam, Vaira Vignesh) "Characterization of powder metallurgy processed magnesium alloys for biomedical implants", Emergent Materials, 2023

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