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Chiral Synthesis of a-phenylpyridylmethanols with Rhizopus arrhizus

Publication Type : Journal Article

Thematic Areas : Biotech

Publisher : Kluwer Academic Publishers

Source : Biotechnology Letters, Kluwer Academic Publishers, Volume 20, p.201-203 (1998)

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Campus : Amritapuri

School : School of Biotechnology

Center : Biotechnology, Phytochemistry Labs

Department : biotechnology

Year : 1998

Abstract : The bioreduction of 2-benzoylpyridine (1a) with Rhizopus arrhizus afforded (S)-(+)-alpha-phenyl-2-pyridylmethanol (2a) in 82% enantiomeric excess (e.e.) while the asymmetric hydrolysis of its racemic acetate resulted in the antipode (R)-(-)-2a with 24% optical purity.

Cite this Research Publication : N. A. Salvi, Udupa, S. R., and Banerji, A., “Chiral Synthesis of a-phenylpyridylmethanols with Rhizopus arrhizus”, Biotechnology Letters, vol. 20, pp. 201-203, 1998.

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