Publication

Abstract : Recent years have seen tremendous interest among researchers in the field of biosensors for the application of medical and agricultural products, processed food, and environmental monitoring. To prepare a stable and reliable biosensor, immobilization of biological responses elements (BRE) plays a critical role. Chitosan, a natural polysaccharide with non-toxic and gellable properties, and the presence of functional groups would act as a suitable substrate material. The presence of functional groups would provide cross-linking moieties increasing the mechanical stability, immobilization of BRE and nanomaterials. Additionally, a chitosan composite/nanocomposite-based biosensor would provide enhanced conductivity and sensitivity of detecting various biological analytes such as glucose, H2O2, antigens, DNA, and biomolecules. This review provides a comprehensive understanding of various strategies of utilizing chitosan as a substrate for various biosensing applications.