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Efficacy of Intranasal Dexmedetomidine Versus Oral Midazolam for Paediatric Premedication

Publisher : Indian J Anaesth

Campus : Kochi

School : School of Medicine

Year : 2017

Abstract : Premedication is an integral component of paediatric anaesthesia which, when optimal, allows comfortable separation of the child from the parent for induction and conduct of anaesthesia. Midazolam has been accepted as a safe and effective oral premedicant. Dexmedetomidine is a selective alpha-2 agonist with sedative and analgesic effects, which is effective through the transmucosal route. We compared the efficacy and safety of standard premedication with oral midazolam versus intranasal dexmedetomidine as premedication in children undergoing elective lower abdominal surgery.

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