Back close

Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet

Publication Type : Journal Article

Publisher : Pakistan journal of pharmaceutical sciences

Source : Pakistan journal of pharmaceutical sciences, Volume 23, p.232-5 (2010)

Url : https://www.researchgate.net/publication/42975554_Formulation_and_evaluation_of_Cetirizine_dihydrochloride_orodispersible_tablet

Campus : Kochi

School : School of Pharmacy

Department : Pharmaceutical Chemistry & Analysis

Year : 2010

Abstract : Cetirizine orodispersible tablets were prepared to achieve quick onset of action and for maximum bioavailability. Tablets were prepared using cetirizine along with camphor and mannitol in the proportion of 1:1:1, 1:1:3, and 1:1:6. The flow property of granules was found to be good for the formulation CZ2 (1:1:3). The hardness and friability of all the formulations were found to be within the standard limit for orodispersible tablets. Disintegration time was found to be rapid in formulation CZ2 (1:1:3).The in vitro dissolution time was found to be 100% in 11 minutes for the formulation CZ2 (1:1:3).

Cite this Research Publication : S. Subramanian, Sankar, V., Manakadan, A., Ismail, S., and Andhuvan, G., “Formulation and evaluation of Cetirizine dihydrochloride orodispersible tablet”, Pakistan journal of pharmaceutical sciences, vol. 23, pp. 232-5, 2010.

Admissions Apply Now