ProgramsView all programs
From the news
- Chancellor Amma Addresses the Parliament of World’s Religions
- Amrita Students Qualify for the European Mars Rover Challenge
Publication Type : Journal Article
Publisher : Infect Disord Drug Targets
Source : Infect Disord Drug Targets, Volume 15, Issue 2, p.76-88 (2015)
Keywords : Antitubercular Agents, Humans, Hydrazones, Microbial Sensitivity Tests, Mycobacterium tuberculosis, Structure-Activity Relationship
Campus : Kochi
School : School of Pharmacy
Department : Pharmaceutical Chemistry & Analysis
Year : 2015
Abstract : Hydrazones are a versatile linker of connecting various classes of organic compounds with a unique structural feature of hydrogen bonding donor and the hydrogen bonding acceptor region. An extensive number of research has been carried out on hydrazone derivatives as a potent class of antitubercular agents. The present review focuses on the chemistry, antitubercular activity and structure activity relationship (SAR) of diverse classes of phenyl and heterocyclic based hydrazones.
Cite this Research Publication : Bijo Mathew, Suresh, J., Ahsan, M. J., Mathew, G. E., Usman, D., Subramanyan, P. N. S., Safna, K. F., and Maddela, S., “Hydrazones as a privileged structural linker in antitubercular agents: a review.”, Infect Disord Drug Targets, vol. 15, no. 2, pp. 76-88, 2015.