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Hydrazones as a privileged structural linker in antitubercular agents: a review.

Publication Type : Journal Article

Publisher : Infect Disord Drug Targets

Source : Infect Disord Drug Targets, Volume 15, Issue 2, p.76-88 (2015)

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Keywords : Antitubercular Agents, Humans, Hydrazones, Microbial Sensitivity Tests, Mycobacterium tuberculosis, Structure-Activity Relationship

Campus : Kochi

School : School of Pharmacy

Department : Pharmaceutical Chemistry & Analysis

Year : 2015

Abstract : Hydrazones are a versatile linker of connecting various classes of organic compounds with a unique structural feature of hydrogen bonding donor and the hydrogen bonding acceptor region. An extensive number of research has been carried out on hydrazone derivatives as a potent class of antitubercular agents. The present review focuses on the chemistry, antitubercular activity and structure activity relationship (SAR) of diverse classes of phenyl and heterocyclic based hydrazones.

Cite this Research Publication : Bijo Mathew, Suresh, J., Ahsan, M. J., Mathew, G. E., Usman, D., Subramanyan, P. N. S., Safna, K. F., and Maddela, S., “Hydrazones as a privileged structural linker in antitubercular agents: a review.”, Infect Disord Drug Targets, vol. 15, no. 2, pp. 76-88, 2015.

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