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Immunoglobulins in carcinoma cervix

Publication Type : Journal Article

Thematic Areas : Medical Sciences

Publisher : Indian Journal of Medical Research

Source : Indian Journal of Medical Research, Indian Council of Medical Research., Volume 59, Number 10-12, p.1653 (1971)

Campus : Kochi

School : School of Medicine

Department : Biochemistry

Year : 1971

Abstract : Serum immunoglobulin levels (IgG, IgA, IgM, IgD and IgE) were estimated in 196 patients with carcinoma of the oral cavity, 172 patients with cervical cancer and 166 patients with breast cancer. The values were compared with those of 50 patients with benign lesions of the breast and cervix and 100 healthy adult controls. Only the serum IgE levels were found to be elevated in the benign group. Serum IgA, IgD and IgE levels were found to be elevated in all the three types of cancers and the levels were found to increase with clinical stage. In carcinoma of uterine cervix IgG levels were also found to be elevated. Immunoglobulins A and D returned to normal after clinical cure whereas IgE remained slightly elevated. IgD and IgE remained high in patients who had residual cancer.

Cite this Research Publication : D. M. Balakrishnan, Talwar, G. P., and K, V., “Immunoglobulins in carcinoma cervix”, Indian Journal of Medical Research, vol. 59, p. 1653, 1971.

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