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Kileine-Levin Syndrome of Periodic Somnolence and Megaphagia Syndrome-A Review

Publication Type : Journal Article

Publisher : Journal of Critical Reviews, Innovare Academics Sciences

Source : Journal of Critical Reviews, Innovare Academics Sciences, Volume 7, Issue 11, p.3453–3457 (2020)

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Keywords : binge eating, increased libido, intermittent hypersomnia, Kleine-Levin Syndrome

Campus : Kochi

School : School of Pharmacy

Department : Pharmacy Practice

Year : 2020

Abstract : Kleine-Levin Syndrome is a sleep disorder which is sporadic and it is characterized by periodic episodes of hypersomnia, cognitive impairment, utmost food craving and increased sexual desire. The definite cause has not been identified and no effective treatments are available even though a well-defined clinical feature is observed. Around 1–5 per million individuals were consistently overwhelmed, and it is noticed that most of the teenagers are the victims of this disorder. In Ashkenazi Jewish population, the prevalence is considerably greater. This article reviews about the clinical symptoms, medical investigations and examinations, differential diagnosis, management and limitations. Mostly supportive treatment preferred, though a few medications that are stimulants which include MODAFINIL can help to subside the clinical manifestations.

Cite this Research Publication : P. Sarah Alexander, G., G. S., and Roshni P. R., “Kileine-Levin Syndrome of Periodic Somnolence and Megaphagia Syndrome-A Review”, Journal of Critical Reviews, vol. 7, no. 11, pp. 3453–3457, 2020.

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