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Publication Type : Journal Article
Publisher : J Biomed Opt,
Source : J Biomed Opt, Volume 12, Issue 3, p.034035 (2007)
Keywords : Algorithms, Breast, Breast Neoplasms, Diagnosis, Computer-Assisted, Elasticity, Humans, Phantoms, Imaging, Spectrum Analysis, viscosity
Campus : Amritapuri
School : School of Engineering
Department : Electronics and Communication
Year : 2007
Abstract : Diffusing wave spectroscopy (DWS), without the use of tracer particles, has been used to study the internal dynamics of polyvinyl alcohol (PVA) phantoms, which mimic the properties of normal and malignant breast tissues. From the measured intensity autocorrelations, the mean square displacement (MSD) of phantom meshing is estimated, leading to the storage and loss moduli of the medium covering frequencies up to 10 KHz. These are verified with independent measurements from a dynamic mechanical analyzer (DMA) at low frequencies. We thus prove the usefulness of DWS to extract visco-elastic properties of the phantom and its possible application in detecting malignancy in soft tissues.
Cite this Research Publication : Ushadevi Amma C., R. Sreekumari Bharat Chandran, R. Mohan Vasu, and Ajay K. Sood, “Measurement of visco-elastic properties of breast-tissue mimicking materials using diffusing wave spectroscopy.”, J Biomed Opt, vol. 12, no. 3, p. 034035, 2007.