Back close

Neuroglia as Targets for Drug Delivery Systems: A Review

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine, Els

Source : Nanomedicine: Nanotechnology, Biology, and Medicine, Elsevier Inc., Volume 13, Number 2, p.667-679 (2017)

Url :

Keywords : Astrocytes, drug delivery system, Microglia, Nanoparticles, Neuroglia, Neurological disorders, Neurology, Neurons, Peripheral nervous system, Targeted delivery systems, Targeted drug delivery, toxicity

Campus : Kochi

School : Center for Nanosciences

Center : Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2017

Abstract : Targeted drug delivery within the nervous system is an emerging topic of research that involves designing and developing vehicular delivery systems that have the ability to target specific neuronal and non-neuronal cell types in the central and peripheral nervous system. Drugs, genetic material, or any other payloads can be loaded onto such delivery systems and could be used to treat, prevent or manage various neurological disorders. Currently, majority of studies in this field have been concentrated around targeted delivery to neurons. However, the non-neuronal cells within the nervous system, collectively called neuroglia, have been largely ignored, though it is well known that they play a significant role in the pathophysiology of almost all neurological disorders. In this review, we present current developments in the specific area of neuroglia targeted delivery systems and highlight the use of polymeric, metallic, liposomal and other delivery systems used for this purpose.

Cite this Research Publication : P. Madhusudanan, Reade, S., and Dr. Sahadev Shankarappa, “Neuroglia as Targets for Drug Delivery Systems: A Review”, Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 13, pp. 667-679, 2017.

Admissions Apply Now