Publication Type:

Journal Article

Source:

Journal of Cell Communication and Signaling, Springer Netherlands, p.1-7 (2015)

URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84949508058&partnerID=40&md5=dd4d453e1355e04401c1ea90e7732a0f

Abstract:

Glutamate metabolism plays a vital role in biosynthesis of nucleic acids and proteins. It is also associated with a number of different stress responses. Deficiency of enzymes involved in glutamate metabolism is associated with various disorders including gyrate atrophy, hyperammonemia, hemolytic anemia, γ-hydoxybutyric aciduria and 5-oxoprolinuria. Here, we present a pathway map of glutamate metabolism representing metabolic intermediates in the pathway, 107 regulator molecules, 9 interactors and 3 types of post-translational modifications. This pathway map provides detailed information about enzyme regulation, protein-enzyme interactions, post-translational modifications of enzymes and disorders due to enzyme deficiency. The information included in the map was based on published experimental evidence reported from mammalian systems. © 2015 The International CCN Society

Notes:

cited By 0; Article in Press

Cite this Research Publication

Y. S.D., S., J., J.K., T., S., G., A.A., K., A., S., T.S., K. Prasad, A., P., B.L., S., and f, G. Ha b, “A pathway map of glutamate metabolism”, Journal of Cell Communication and Signaling, pp. 1-7, 2015.