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Synthesis and characterization of polysaccharide hydrogel based on hydrophobic interactions

Publication Type : Journal Article

Thematic Areas : Advanced Materials and Green Technologies

Publisher : Journal of Applied Polymer Science

Source : Journal of Applied Polymer Science, John Wiley and Sons Inc., Volume 136, Issue 25, Number 25 (2019)

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Keywords : Amides, biocompatibility, biodegradable, Biodegradable polymers, Biomaterials, Biomedical applications, Biopolymers, Carboxymethyl cellulose, Cross-linked hydrogels, Crosslinking, Deionized water, Hydrogels, Hydrophobic interactions, hydrophobicity, Mechanical properties, Medical applications, Polysaccharide hydrogels, Synthesis and characterizations, Thermo-sensitive hydrogel

Campus : Coimbatore

School : Department of English and Languages, School of Engineering

Center : Center for Excellence in Advanced Materials and Green Technologies, Center for Industrial Research and Innovation (ACIRI)

Department : Civil

Verified : No

Year : 2019

Abstract : Hydrogels based on hydrophobic, or micellar interactions, are physically crosslinked hydrogels which are an attempt to overcome the poor mechanical properties of traditional, chemically crosslinked gels, such as low shear strength. We have prepared a polysaccharide-based hydrogel with physical crosslinks via hydrophobic interactions. In this work, we have synthesized hydrogel by grafting a hydrophobic moiety dioctylamine onto hydrophilic precursor carboxymethyl cellulose (CMC) through an amide bond formation, where 33% of the carboxyl group in CMC was reacted with dioctylamine. The thermosensitive hydrogel can arrest 100 mL of deionized water per gram of gelator within few seconds. It showed the moderate rheological property. The hydrogel is nontoxic and does not show any adverse to human hemoglobin. It is a CMC based a unique gelator with high biocompatibility represent to be useful materials for biomedical application. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47665. © 2019 Wiley Periodicals, Inc.

Cite this Research Publication : R. Fredrick, Podder, A., Viswanathan, A., and Bhuniya, S., “Synthesis and characterization of polysaccharide hydrogel based on hydrophobic interactions”, Journal of Applied Polymer Science, vol. 136, no. 25, 2019.

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