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Therapeutic Potential of Voltage Gated Calcium Channels

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Mini Reviews in Medicinal Chemistry

Source : Mini Reviews in Medicinal Chemistry, Volume 8, Number 12", publication date ="2008-10-01T00:00:00, p.1285-1290 (2008)

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Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2008

Abstract : Voltage-gated Calcium channels (VGCCs) play important roles in neurotransmitter release, excitationcontraction coupling, hormone secretion, and a variety of other physiological processes. Currently, there exist ion channel therapeutics for anxiety, epilepsy, hypertension, insomnia and pain. There is limited amount of study in this area despite their relevance to human disease and VGCCs remain considerably underexploited. The present review mainly focuses on calcium channel blockers (CCBs), especially for L-type channels and T-type channels, and therein lie some of the opportunities and advantages associated with VGCCs as drug targets.

Cite this Research Publication : Dr. Gopi Mohan C. and Gandhi, T., “Therapeutic Potential of Voltage Gated Calcium Channels”, Mini Reviews in Medicinal Chemistry, vol. 8, pp. 1285-1290, 2008.

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