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Pathogenesis and life cycle of herpes simplex virus infection-stages of primary, latency and recurrence

Publication Type : Journal Article

Publisher : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

Source : Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, Elsevier Ltd (2016)

Url : https://www.scopus.com/inward/record.uri?eid=2-s2.0-84959306024&partnerID=40&md5=b3aa441f0bdb1cc3d90aa880975b5bf4

Campus : Kochi

School : School of Dentistry

Center : Amrita Institute of Medical Science

Department : Oral Medicine and Radiology

Year : 2016

Abstract : Aims and objectives: (1) To understand the molecular level mechanism involved in immune evasion leading to primary HSV infection. (2) To explain the neuronal latency of herpes simplex virus. (3) To explain the reason for the specificity in the sites of primary and recurrent HSV lesions. Methods: A systematic review was done to understand the molecular level mechanism involved in primary, latency and recurrent herpes simplex infections. We prepared this article by compiling the data from various textbooks, literatures and PubMed, Embase, and EBSCOhost databases. Results and conclusion: Herpes simplex virus is a highly contagious human pathogen that has widespread infections in the oro-facial region which is associated with HSV-1. This single review article can provide the entire knowledge about the pathogenesis, its interesting property of latency and clinical features of HSV infection under one tree. Thus, this article enlightens the dental professionals with an adequate knowledge about the pathogenesis, clinical manifestations and specific sites of primary and recurrent lesions which will highly help them in timely diagnosis, management and also for controlling the spread of infection. © 2016 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI./

Cite this Research Publication : Dr. Sreeja P. Kumar, Dr. Marina Lazar Chandy, Shanavas, Mb, Khan, Sc, and Suresh, K. Vd, “Pathogenesis and life cycle of herpes simplex virus infection-stages of primary, latency and recurrence”, Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 2016.

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