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The proposed work envisages the fabrication of microfluidic lab-on-a-chip (LOC) module for non-enzymatic sensing of glucose, cholesterol and creatinine using a single device. This consists of a disposable LOC and a non-disposable electronics module. The use of non-enzymatic sensing module helps to achieve longer shelf life, eliminating the need for stringent storage conditions. This reduces the cost and time of analysis considerably. The point of care diagnostic device provides an effective alternative for the existing expensive and time consuming clinical analysis performed by a trained clinical lab technician. This would thereby enable access to low-cost medical diagnostics even to underprivileged sections of the society.