• Application of nanomaterials to cell-based targeted diagnostics and regenerative medicine at a clinical level is an evolving domain that is of substantial interest to the medical scholars worldwide.

    cell-targeted-diagnostics-and-therapy-using-nanomaterials
  • Fusion transcripts are known to occur in cancerous cells across a range of cancers and might play important roles in the pathophysiology of cancer. In developing newer strategies to combat cancer, therapeutic knock down of fusion transcripts by RNA interference technology is being considered for its potential benefits in targeting cancerous cells.

    fusion-transcripts-in-cancer-and-the-potential-to-inhibit-by-rna-interference
  • Asymptomatic hyperparathyroidism is not well recognized in Indian population and is considered rare. Estimation of serum calcium level is not part of routine comprehensive health checkup.

    population-survey-of-asymptomatic-hyperparathyroidism-in-kerala
  • This project deals with the development of a non-destructive technology for the detection of biological and chemical food toxins including bacteria, virus, small molecules toxins, and genetically modified foods using nanotechnology enabled Surface Enhanced Raman Scattering (SERS).

    chemical-and-biological-food-toxins-using-surface-enhanced-raman-scattering-sers-
  • The project 'Oncogene Sensing and Finger Printing from Saliva Using Nanotechnology' deals with Raman spectroscopic detection of cancer biomarkers from human tissues and bio-fluids.

    oncogene-sensing-and-finger-printing-from-saliva-using-nanotechnology-enabled-using-raman-spectroscopy
  • The current study will enable the elucidation of global miRNA expression profiles and identification of miRNA targets in response to intervention with chemopreventive phytochemicals in liver cancer. This will enable a better understanding of miRNA dysregulation and identify novel biomarkers for preventive or therapeutic intervention in liver cancer.

    modulation-of-microrna-and-protein-signatures-in-hepatocellular-carcinoma-by-chemopreventive-phytochemicals
  • The crucial role of hands on experiments in the STEM curriculum to motivate and deepen understanding is universally accepted. In India, many schools lack equipment in science labs and in rural areas there is a lack of teachers depriving students of STEM education.

    measuring-learning
  • A project under MHRD ERP, Amrita Display Information and Visualization Engine (Amrita DIVE) uses ROLAP technology to gather information from multiple LMS/CMS engines and then uses advanced visualization techniques to provide graphed information that allows educators to understand the pattern and usage of content used by Indian universities. 

    amrita-display-information-and-visualization-engine-amrita-dive-
  • Docking studies are computational techniques for the exploration of the possible binding modes of a substrate to a given receptor, enzyme or other binding site. The application of computational methods to study the formation of intermolecular complexes has been the subject of intensive research during the last decade.

    computational-chemistry-amp-molecular-docking-studies
  • The main objective of this project is to monitor and control the machining process during ultra-precision machining of titanium alloys. Using advanced signal processing techniques, the hidden information in the acoustic emission signal is extracted to predict the machining parameters with high levels of accuracy. The features from the signal are extracted and a set of predominant features is selected using dimensionality reduction techniques.

    process-monitoring-and-control-of-ultra-precision-machining-of-titanium-alloys
  • This project involves a controlled and well-characterized material process development for the preparation of carboxymethyl chitin and chitosan derivatives for applications in the biomedical area. Chitin and Chitosan are known to be natural biopolymers and are non-toxic, biodegradable and biocompatible. In the last decade, chitin and chitosan derivatives have become the focus of interest in biomedical and biopharmaceutical research.

    preparation-of-carboxymethyl-chitin-and-chitosan-derivatives
  • This project involves application of a new technique using a proteomics approach to sensitively identify molecules of therapeutic significance in Cerebral Spinal Fluid (CSF) samples.

    identification-of-novel-cell-surface-molecules-of-therapeutic-significance-in-central-nervous-system-leukemia
  • Virtual Lab: Amrita Vishwa Vidyapeetham is transforming the face of higher education and research, through a revolutionary new educational tool – virtual labs. The VALUE Initiative is a project dedicated to developing these virtual labs in various science and engineering disciplines. Virtual labs are media-rich online learning environments, which allow users to conduct physical laboratory experiments in a computer-simulated environment. This innovative new educational technique is enabling experimentation beyond the boundaries of traditional laboratories

    value-virtual-simulation-labs
  • VALUE Virtual Chemistry laboratories introduce a new dimension to the chemistry lab. Virtual labs provide a number of benefits to both the student and teacher. Virtual experiments allow educational institutes to take advantage of vast savings from reduced consumption in chemical supplies and reduced costs that result from accidental breakages.

    chemistry-virtual-labs
  • The project titled Development of New and Efficient Photo Sensitizer for Dye Solar Cell funded by DRDO.

    development-of-new-and-efficient-photo-sensitizer-for-dye-solar-cell
  • Amrita University is creating comprehensive Mechanical Engineering Virtual Labs in the following areas: Mechanics of Solids, Wind Energy, Solar Thermal Energy, and Energy Storage. Each lab consists of 8 to 10 experiments. All experiments have a common web platform where students can view experiments via a web interface happening in real-time with a web-cam. 

    mechanical-engineering-virtual-labs
  • Comprehensive study of threats, their operational architecture, and adoption of threat modeling for their classification, form the foundation for development of secure technologies for cloud. Cloud platforms today assist providers in controlling and managing the customer VMs. In addition, they also help monitor and manage cloud performance. 

    threat-modeling-trust-modeling-and-development-of-secure-platform-in-cloud-environments
  • Virtual Physics Labs have sophisticated simulations that enable the users to conduct a vast array of physics experiments. Users can work with interactive electronic components to create electric circuits, conduct oscillatory experiments on different planets, or interact with specialized virtual equipment such as a Laser Beam Emitter. All this becomes available to the user simply with a computer and an internet connection.

    physics-virtual-labs
  • This project is ongoing as part of the Amrita E-Learning Research Center. The goal of this project is to develop solutions for content based search and retrieval of multimedia E-Learning material.

    indexing-and-searching-e-learning-content
  • The dynamics of spatially structured populations (metapopulations) have been widely studied over the last few decades. For the sake of simplicity, most of these studies assume that all the constituent local populations (subpopulations) experience similar rates of migration (immigration and emigration). Although it is intuitively obvious that nothing in nature constrains the migration rates to be symmetric, i.e.

    theoretical-and-empirical-investigations-on-the-interaction-of-asymmetric-migration-and-intrinsic-growth-rate-on-the-dynamics-of-laboratory-metapopulations-of-drosophila-melanogaster
  • There are more than 2.5 million cancer patients in India at any given time, of which the frequency of breast and ovarian cancer cases has increased. Although there are many possible reasons, reversible phosphorylation of proteins, mediated by receptor tyrosine kinases (RTK) such as VEGF and HER2/neu receptors play a crucial role on different cellular processes associated with cancer pathogenesis.

    cancers-treated-with-vegf-and-her-2-neu-receptor-tyrosine-kinase-inhibitors
  • Wordnet is an online lexical reference system. Its design is inspired by current psycholinguistic and computational theories of human lexical memory. Nouns, verbs, adjectives and adverbs are organized into synonymous sets, each representing one underlying lexicalized concept. Different semantic relations link the synonymous sets. Wordnet is neither a traditional dictionary nor a thesaurus but combines features of both types of lexical reference resources.

    development-of-source-code-methodologies-plagiarism-detection-engine
  • This project is an initiative of Ministry of Communication and Information Technology. The principal investigator of the project is Dr. Soman K. P., Professor and Head, Amrita Center for Computational Engineering and Networking (CEN). 

    development-of-malayalam-wordnet
  • After broad separation of tannins as lead complex from the SBT extract , flavonoid glycosides (in the supernatant) were subjected to column chromatography using SiO2 and LH-20. Partially purified fractions were put for preparative HPLC and glycosides were isolated.

    molecular-structural-studies-of-complex-natural-products-by-lcms-and-uv-spectrophotometry
  • The objective of this study is to develop an epidemiological model for school-based interventions to modify cardiovascular risk profile. The study aims to identify ethical and practical issues with possible solutions in conducting such a study in an Indian setting.

    development-of-an-epidemiological-model-to-modify-cardiovascular-risk-profile-in-children
  • AMMACHI Labs uses computerized vocational education training (cVET) to make education accessible and interesting. The smart classroom concept was introduced into the many training centers across India to enable a learning environment that would scale up skill training, maximize student participation and enhance learning.

    e-content-for-skill-development-and-education
  • Aerospace Engineering Department at Amrita University, Coimbatore Campus, acquired a MiG-23, a fighter-aircraft, from the Indian Ministry of Defense. With this acquisition, students are able to better study the functions and workings of various subsystems of an aircraft. They have an opportunity to lay hands on a real-life aircraft and its subsystems; they get a first-hand experience. The majority of its subsystems are already in place. The Aerospace Engineering Department was started at Amrita in 2007 and over 190 students are currently enrolled in the Aerospace B-Tech program. The department has set up state-of-the-art labs, including an Aerodynamics Lab, Aerospace Structures Lab, Propulsion Lab, and Flight Dynamics and Control Lab.

    mig-aircraft-and-kamov-helicopter
  • Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis.

    diversity-oriented-synthesis-applications-to-flavonols-flavones-isoflavones-and-biflavones
  • In the Phytochemistry laboratory, development, analysis, and optimization of technical processes for target dependent bioactive compound isolations and assays are carried out. A brief account is given below.

    process-development-for-isolation-and-characterization-of-phytochemicals
  • There are a wide range of underutilized plants with well known nutritional and medicinal properties. They have the potential for further promotion as they are locally available or are byproducts or waste materials. They are culturally accepted and often well established component of life systems and diets. Some of the isolated phytochemicals from them have commercial value.

    Seabuckthorn

    value-addition-to-underutilized-biosources
  • Seabuckthorn (SBT), (Hippophae L.) are deciduous shrubs in the genus Hippophae, family Elaeagnaceae. In addition to the nutritionally active constituents, many clinically important activities of seabuckthorn (SBT), such as beneficial effects on skin, cardiovascular diseases, diabetes, wound healing, cancer chemopreventive action, antiviral activity, sun screen and radioprotection have been established.

    seabuckthorn-a-repository-of-bioactive-phytochemicals
  • The project titled Synthesis, characterization and liquid Crystalline Studies of Azo and Schiff Base Containing Porphyrin Complex funded by CSIR.

    synthesis-characterization-and-liquid-crystalline-studies-of-azo-and-schiff-base-containing-porphyrin-complex
  • Research in modern chemistry attempts to find materials that can act as superior switches and transistors. One of the most exciting, yet challenging fields of research, is the design and synthesis of multifunctional compounds that have desirable and predictable properties of luminescence, transport of information, catalytic activity and macroscopic ordering in mesophase.

    synthesis-characterization-and-liquid-crystalline-studies-of-schiff-base-containing-porphyrin
  • The project titled "Value addition to seabukthorn through isolation & characterisation of pharmacologically active compounds" is funded by Department of Biotechnology. Dr. Bipin Nair is the Principal Investigator of the project.

    value-addition-to-seabukthorn-through-isolation-amp-characterisation-of-pharmacologically-active-compounds
  • Dispersion of nanocarbon forms and metal nanoparticles in a conducting polymer matrix facilitates coating of such materials. Different nanocarbon materials such as single walled carbon nanotube (SWCNT), double walled carbon nanotube (DWCNT), multi walled carbon nanotube (MWCNT), and graphene are being synthesized using Radio Frequency (RF) Catalytic Chemical Vapor Deposition (CCVD).

    novel-nanocomposites-with-unusually-high-conductivity-for-microwave-absorption-development-of-carbon-intrinsically-conducting-polymer-c-icp-and-c-icp-metal-nanocomposites
  • This research contributed to the deployment of world’s first wireless sensor network for landslide detection. This research was initially part of WINSOC project, funded by the European Commission under FP6 program. The Government of India plans to deploy this system in all landslide prone areas of India, furthering three projects with DeitY, DST, and MoES.

    development-of-a-real-time-wireless-sensor-network-for-landslide-monitoring
  • Diabetic wound healing is a challenging problem to solve as it requires the integration of interdependent processes that involve signal transduction input from inflammation, cell migration, cell proliferation, cell differentiation and production of extracellular protein components.

    molecular-mechanisms-in-impaired-wound-healing
  • The objective of the work was to develop aluminum alloys containing lithium, copper, and zirconium for aerospace applications. Moderately thick deposits of binary and ternary alloys of aluminum with lithium, copper and zirconium were successfully electrodeposited. This was achieved at room temperature through the use of low cost ionic liquid containing AlCl3 and triethylammine hydrochloride (Et3NHCl).

    electrodeposition-of-aluminium-lithium-alloys-for-cryo-and-space-applications
  • The focus of this project is to develop a biofuel cell that is capable of powering medical devices and mobile electronic devices. This research involves fabricating 3-D nanoengineered electrodes using CVD grown carbon nanotubes and electrodeposited nanowires, investigating the direct electron transfer between nanoelectrodes and enzyme redox center, and demonstrating the functionality of miniaturized high power density biological fuel cell.

    electro-nanoprocessing-of-semiconductor-nanotube-arrays-for-high-efficiency-photovoltaics
  • India’s first landslide laboratory setup, Funding Agency: European commission,  Department of Information Technology (DIT) & Amrita University, Laboratory Setup in 2008, Lab serves as a testbed for development and validation of the systems deployed in the landslide prone areas, such as the wireless sensor nodes, signal conditioning circuits, power circuits, sensors and others.

     

    landslide-lab-setup
  • Preliminary  studies  have  been  carried  out  using  flexible  laminates prepared  from  different  types  of  PET  films  and  UHMWPE (Dyneema)  fabric  using  polyurethane  based  adhesive.  Peel strength,  Lap  shear  strength  and  helium  leak  rate  of  the  samples were  studied.  The  effect  of  plasma  treatment  of  Dyneema  fabric  on the  adhesion  properties  was  analyzed.  Discussions  held  with  ISRO scientists  provided  focus  to  the  subsequent  studies.

    polymer-nanocomposites-for-inflatable-space-structures
  • The basic methodology of this project envisages capturing core patient identifying information with details of clinical stage, types of treatment (with all particulars), and follow-up parameters as per standards specified. The results are evaluated at annual reviews by The National Cancer Registry Program, Indian Council of Medical Research.

    patterns-of-care-and-survival-studies-in-head-amp-neck-cancer-cancer-cervix-cancer-breast-all-india-study-national-cancer-registry-project
  • This research project identifies an appropriate combination of metal-elastomeric module configuration, using multi-layer shear damped viscoelastic approach, for mitigating the structure-bound vibrations on to the sensitive equipment. The composites are made of a metal (aluminium), and an elastomer (natural rubber and silicone rubber).

    analysis-and-evaluation-of-multilayer-shear-damped-viscoelastic-treatments-for-launch-vehicle-applications
  • WINSOC is a European Commission funded collaborative research project comprised of 11 academic research institutes and industry partners based in India and Europe. This project developed a novel method of wireless sensor network that mimics biological systems. 

    winsoc-wireless-sensor-networks-with-self-organization-capabilities-for-critical-and-emergency-applications
  • Induction motors at light load run at low power factor and low efficiency. But  if  the  stator  supply  voltage  is  reduced  at  light  load  condition,  both the  efficiency  and  power  factor  can  be  improved  owing  to  reduction  in magnetizing  current  and  core  loss.  The  proposed  energy  saver  is  a thyristorized  phase  control  working  in  feed  back  mode.

    development-of-energy-saver-for-induction-motors
  • The  project  aims  to  develop  elastomer-based  polymer  nanocomposites [PNC]  for  use  as  engine  gimbal  control  system  bladders,  critical  components in  a  launch  vehicle.  Currently  nitrile  rubber  [NBR]  compounds  based  on microcomposites  are  being  used  for  the  purpose.  Resistance  to  crack formation  under  dynamic  conditions  and  compatibility  with  oil  and  gas permeability  are  the  important  characteristics  of  these  bladders.

    elastomer-based-nanocomposites-for-control-system-bladders
  • All the state of the art methods of image fusion techniques were compiled and implemented as easy to use software.

    development-of-image-fusion-techniques-and-measurement-methods-to-assess-quality-of-fusion
  • Amrita Research Labs has developed this integrated telemedicine solution for linking various clinics and hospitals located in the remote areas of India with Amrita Institute of Medical Sciences and Research Center (AIMS), Kochi. Telemedicine, reduced to its simplest form, is connecting geographically separate health care facilities via telecommunications, video, and information systems.

    center-for-digital-health-wireless-telemedicine-
  • METASIM is a highly distributed collection of simulation tools connected by a series of translators that access a common database.

    metasim
  • In a synergistic combination arising out of its partnership with Media Lab Asia, Amrita has developed an innovative wireless telemedicine system and network for digital health at every doorstep. Amrita’s wireless telemedicine instantly enables a variety of common biomedical and public healthcare diagnostic devices to capture body parameters directly from people’s office or home and immediately transmit wirelessly through a combination of ultra high-speed WiFi and satellite networks to the 1450-bed all digital, super specialty hospital, AIMS, in Kochi.

    digital-health-at-every-doorstep-using-integrated-high-bandwidth-wireless-communication-networks

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