• In this project, we will use EEG recordings to control robotic arm by extracting left and right side motor imagery movement patterns. We will develop and use feature extraction methods to extract the required features from the pre-processed signal data.

    designing-a-bmi-based-robotic-arm-using-eeg-and-motor-articulation-control
  • Plants are widely used for wastewater treatment, but there are concerns that the plants might act as a reservoir of the pathogens. This project aims at using bacteriophages to specifically kill the pathogenic bacteria and use the roots of the aquatic plants as possible adsorbent material for bacteriophages.

    synergistic-effects-of-plants-and-bacteriophages-in-wastewater-treatment
  • Caenorhabditis elegans is a widely used model nematode for developing anti-helmintic drugs. We have used that for developing safe waste management strategy against soil transmitted helminthes contributing most significantly to global burden of infection. Sludge accumulation is the major problem in various parts of the world. Composting can be a cost-effective solution and can be potentially augmented with inherent sewage lytic agents.

    c-elegans-as-a-model-to-develop-anti-helmintic-strategies-in-solid-waste-management
  • Triclosan is a widely used biocide to prevent Methicillin-resistant Staphylococcus aureus (MRSA) outbreaks in hospitals. Lately, long term exposure to triclosan has resulted in certain strains showing susceptibility and thereby resistance and even enhancement of colonisation has been reported. Adhesion to host tissue is achieved by a large family of staphylococcal surface proteins that bind with varying degrees of specificity to host matrix proteins.

    label-free-quantitative-proteomics-analysis-to-study-the-effect-of-triclosan-on-delta-haemolysin-a-haemolytic-factor-of-methicillin-resistant-staphylococcus-aureus
  • Lifespan is a biological process regulated by several genetic pathways. One strategy to investigate the regulation of lifespan is to use small molecules to perturb age-regulatory pathways. Here we plan to screen compounds in a biphasic approach. To find compounds that extend and decrease lifespan of C. elegans. To date, a number of molecules are known to extend or decrease lifespan in various model organisms and are used as tools to study the biology of aging and anthelminthic.

    screening-for-compounds-with-lifespan-altering-effect-on-caenorhabditis-elegans-and-gene-expression-microarray-data-based-computational-drug-repurposing
  • A biofilm is an assemblage of microbial cells that is irreversibly associated (not removed by gentle rinsing) with a surface and enclosed in a matrix of primarily polysaccharide material. Noncellular materials such as mineral crystals, corrosion particles, clay or silt particles, or blood components, depending on the environment in which the biofilm has developed, may also be found in the biofilm matrix.

    bacterial-glycan-recognition-by-lectins
  • Antimicrobial textiles is of high market value for their potential use in different sanitary causes such as hospital clothes, bed linens, wound healing bandage, sanitary napkins etc. We checked the literature to find out the possible solutions in this regard which ranged from impregnation of the textile material with natural products, dyes and nanomaterials. They are generally costly and very often ineffective against antibiotic resistant infections.

    antimicrobial-textiles-using-phage-and-other-lytic-agents
  • The Universal Stress Protein (USP) superfamily represents a growing set of small cytoplasmic proteins whose expression is affected by a wide variety of internal or external environmental stresses.

    role-of-universal-stress-protein-in-bacterial-pathogenesis
  • Bacteriocins are antimicrobial peptides produced by bacteria that kill or inhibit the growth of other bacteria. Bacteriocins differ from most therapeutic antibiotics in being proteinaceous and generally express a narrow specificity of action against strains of the same or closely related species.

    studies-on-antagonistic-effects-of-partially-purified-bacteriocins-from-microflora-of-fermented-vegetables-against-enteric-pathogens
  • Enteric pathogens in the sewage are the reason for a variety of diseases throughout the world. Here in this project we use recombinant protein expression as a remedy to kill enteric pathogens present in sewage. One way to kill these pathogens is by degrading their cell walls using cell wall hydrolases like amidase. We isolated the plasmid from the transformed S. aureus with the pTX15 vector containing the amidase, using Qiagen plasmid isolation kit.

    expression-of-recombinant-enzymes-against-enteric-pathogens
  • The exploration of endophytes is still an emerging field. Almost all plants seem to deliver endophytes with promising contents and activities. Simarouba glauca has a long history in herbal medicine as antiparasitic, antidysentric, antipyretic and anti cancerous agent in many countries.

    in-vitro-studies-on-pharmacological-potential-of-mycoendophyte-of-simarouba-glauca
  • This research project seeks to bring together biomass based biochars and hydrochars from rice husk waste product to remove heavy metals and other contaminants from industrial and domestic wastewater that makes its way untreated or only partially treated into rivers and streams.

    an-innovative-green-technology-for-treating-municipal-and-industrial-wastewater-entering-rivers-and-streams

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