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Blood Oxygen Level Dependent (BOLD) signals are the responses of functional magnetic resonance imaging techniques used to understand brain state and function in neurology. As an early role in translational neuroscience, Amrita mind brain center works on reconstructing fMRI BOLD and neurovascular coupling models based on large-scale neural microcircuit models, allowing clinical neuroscientists to connect back to physiological experiments and existing data-driven neuron and network models. This project was also part of EU Human Brain Project voucher call, BOLDSim.