Course

Unit I

1. Cell and Molecular Biology: Definitions theory and basics and Applications.
2. Cell and Molecular Biology: History and Summation.
3. Properties of cells and cell membrane.
4. Prokaryotic versus Eukaryotic
5. Cellular Reproduction
6. Chemical Foundations – an Introduction and Reactions (Types)

(10 Hours)

Unit II

1. DNA and the Flow of Molecular Information
2. DNA Functioning
3. DNA and RNA
4. Prokaryotic versus Eukaryotic
5. Types of RNA Cellular Reproduction
6. Transcription and Translation

(10 Hours)

Unit III

1. Proteins and Amino Acids : Definition
2. Protein Structure
3. Regularities in Protein Pathways
4. Cellular Processes
5. Positive Control and significance of Protein Synthesis

(10 Hours)

Unit IV

1. Science of Genetics
2. Transgenics and Genomic Analysis
3. Cell Cycle analysis
4. Mitosis and Meiosis
5. Cellular Activities and Checkpoints

(08 Hours)

Unit V

1. Cell Signals: Introduction
2. Receptors for Cell Signals
3. Signaling Pathways: Overview
4. Misregulation of Signaling Pathways
5. Protein-Kinases: Functioning

(07 Hours)

‘Cell and molecular biology – Theory’ is a course offered in the eighth semester of B. Pharm program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 45 Hours

Scope:

1. Cell biology is a branch of biology that studies cells – their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division, death and cell function.
2. This is done both on a microscopic and molecular level.
3. Cell biology research encompasses both the great diversity of single-celled organisms like bacte- ria and protozoa, as well as the many specialized cells in multi-cellular organisms such as humans, plants, and sponges.

Objectives:

Upon completion of the subject student shall be able to

1. Summarize cell and molecular biology history.
2. Summarize cellular functioning and composition.
3. Describe the chemical foundations of cell biology.
4. Summarize the DNA properties of cell biology.
5. Describe protein structure and function.
6. Describe cellular membrane structure and function.
7. Describe basic molecular genetic mechanisms.
8. Summarize the Cell Cycle

Recommended Books (Latest Editions)

1. W.B. Hugo and A.D. Russel: Pharmaceutical Microbiology, Blackwell Scientific publications, Oxford London.
2. Prescott and Dunn., Industrial Microbiology, 4th edition, CBS Publishers & Distributors, Delhi.
3. Pelczar, Chan Kreig, Microbiology, Tata McGraw Hill edn.
4. Malcolm Harris, Balliere Tindall and Cox: Pharmaceutical Microbiology.
5. Rose: Industrial Microbiology.
6. Probisher, Hinsdill et al: Fundamentals of Microbiology, 9th ed. Japan
7. Cooper and Gunn’s: Tutorial Pharmacy, CBS Publisher and Distribution.
8. Edward: Fundamentals of Microbiology.
9. N.K.Jain: Pharmaceutical Microbiology, Vallabh Prakashan, Delhi
10. Bergeys manual of systematic bacteriology, Williams and Wilkins- A Waverly company
11. B.R. Glick and J.J. Pasternak: Molecular Biotechnology: Principles and Applications of Recombinant DNA: ASM Press Washington D.C.
12. RA Goldshy et. al., : Kuby Immunology.