Cancer Biology

Our laboratory studies the process of cell death. Upon the exposure of different kind of stress (like UV Radiation, Starvation, Xenobiotics etc) the cell takes on various death pathways like Apoptosis, Autophagy, Necrosis. Apoptosis has been the far and widely studied cell death pathway with membrane blebbing, activation of caspases and cellular and nuclear fragmentation. Recent studies on cell death shows the emergence of several non apoptotic pathways like Paraptosis, Pyroptosis, Ferroptosis etc.