Publication Type:

Journal Article

Source:

Chakkaravarthi et al.(2008, 2010). (2010)

Abstract:

A solution of 1-(2-(bromomethyl)-1-(phenylsulfonyl)-1H-indol-3-yl) propan-1-one (5 g, 12.31
mmol) and triphenylphosphine (3.5 g, 13.54 mmol) in dry THF (100 ml) was refluxed for 6 h.
After consumption of the starting material, the solvent was removed under vacuum and the
solid washed with diethyl ether to give the phosphonium salt. Then, the mixture of
phosphonium salt (8 g, 11.97 mmol), 4-chloro-2-nitrobenzaldehyde (2.45 g, 13.17 mmol)
and K2CO3 (3.30 g, 23.95 mmol) in DCM (70 ml) was stirred at room temperature for 24 h

Cite this Research Publication

Dr. Yamuna R., ,, Chakkaravarthid, G., ,, and Saravanan, V., “biological ”, Chakkaravarthi et al.(2008, 2010)., 2010.