Generation of Induced Pluripotent Stem (iPS) Cells from Genetically Altered Somatic cells

Induced pluripotent stem cells (iPSc) are somatic cells that have been reprogrammed to a pluripotent state. These iPSc have similar characteristics to embryonic stem cells and hold great promise in various aspects of research. The aim of this study is to develop patient specific stem cells to understand disease mechanism and identify drugs that will prevent malignant transformation.