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Dr. Hisham Ahamed

Associate Professor , Department of Cardiology, School of Medicine, Kochi

Qualification: DM, MD
hishama@aims.amrita.edu

Bio

Dr Hisham Ahamed completed his medical degree from J.S.S Medical College, Mysore and was awarded the Rajiv Gandhi University of Health Sciences Gold Medal for the highest aggregate marks in pathology during his training. He subsequently went on to pursue a career in internal medicine at Sri Ramachandra University, Chennai which is one of the largest tertiary care referral centers in South India. He successfully completed his internal medicine residency program at Chennai in 2008 and received the Gold Medal for the best outgoing resident in internal medicine. Having decided to focus on cardiovascular medicine, he joined the Amrita Institute of Medical Sciences and Research, which had one of the most prestigious cardiovascular training programs in the country. During his cardiology training, he also received the Gold Medal for the best academic performance amongst cardiology residents. Dr Hisham went on to complete an interventional cardiology fellowship at Amrita and has been a permanent faculty at the institute since 2012. He has also obtained a fellowship in advanced cardiovascular imaging (cardiovascular MRI) from Lisbon and is actively involved in managing the advanced cardiovascular imaging protocols at Amrita.

Hypertrophic cardiomyopathy and other inherited cardiomyopathies are a key area of research for Dr Hisham. In 2013, under the mentorship of Dr Barry.J.Maron from Tufts HCM Center in Boston, he was able to establish the first and largest center of excellence in India, with respect to hypertrophic cardiomyopathy (HCM) at the Amrita Institute of Medical Sciences and Research, Kochi. It has now become the preferred destination for HCM patients all across India for their comprehensive evaluation and management needs. The Amrita HCM center is complimented by a state-of-the-art cardiovascular genomics division which is lead by Dr Hisham. He was also instrumental in establishing the first cardio-oncology division in India at the Amrita Institute, which offers a holistic approach and state of the art evaluation protocols which identifies the cardiovascular risk factors of cancer patients. This was established under the umbrella of the International Cardio-Oncology Society (ICOS).

Dr Hisham currently serves as the director of the Amrita HCM center, the co-director of the Amrita Amyloid Center and the clinical lead of cardiovascular genomics in his capacity as associate professor of cardiology and internal medicine at the Amrita Institute of Medical Sciences and Research, Kochi.

Publications

Case Reports

Year : 2023

Eosinophilic myocarditis in the era of multi-modality cardiac imaging: A case report

Cite this Research Publication : Tanmay Sandeepak Kulkarni, C Rajiv, A Hisham, M Navin, R Kannan, S Shanmugha, ‘Eosinophilic myocarditis in the era of multi-modality cardiac imaging: A case report’, IHJ Cardiovascular Case Reports (CVCR),2023.

Journal Article

Year : 2024

Identification of high-risk imaging features in hypertrophic cardiomyopathy using electrocardiography: A deep-learning approach

Cite this Research Publication : Richard T Carrick, Hisham Ahamed, Eric Sung, Martin S Maron, Christopher Madias, Vennela Avula, Rachael Studley, Chen Bao, Nadia Bokhari, Erick Quintana, Ramiah Rajesh-Kannan, Barry J Maron, Katherine C Wu, Ethan J Rowin, Identification of high-risk imaging features in hypertrophic cardiomyopathy using electrocardiography: A deep-learning approach, Heart Rhythm,2024

Publisher : Elsevier

Year : 2024

Fabry Cardiomyopathy with Left Ventricular Apical Aneurysm and End-stage Heart Failure

Cite this Research Publication : Hisham Ahamed, Rajesh Kannan, Marsha Barretto, Chris Ann, Fabry Cardiomyopathy with Left Ventricular Apical Aneurysm and End-stage Heart Failure, Journal of Cardiovascular Magnetic Resonance,2024.

Publisher : Elsevier

Year : 2024

Previous Next Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier

Cite this Research Publication : Hisham Ahamed, Arun Gopi, Effect of Flecainide on Multifocal Ectopic Purkinje-Related Premature Contractions in an R814W SCN5A Carrier, JACC: Case Reports ,2024.

Year : 2024

PO-04-094 IMPROVED PREDICTION MODEL FOR RISK OF ATRIAL FIBRILLATION IN HYPERTROPHIC CARDIOMYOPATHY : LEAP-HCM SCORE

Cite this Research Publication : Muthiah Subramanian, Hisham Ahamed, Radhika Korabathina, Sachin D Yalagudri, Daljeet K Saggu, Sridevi Chennapragada, Calambur Narasimhan, PO-04-094 IMPROVED PREDICTION MODEL FOR RISK OF ATRIAL FIBRILLATION IN HYPERTROPHIC CARDIOMYOPATHY : LEAP-HCM SCORE, Elsevier,2024

Publisher : Elsevier

Year : 2024

127 A comparative analysis of conduction system pacing and conventional pacing in patients undergoing atrioventricular node ablation: a systematic review and meta-analysis Free

Cite this Research Publication : Akash Mavilakandy, Ahmed Abdelrazik, Khaled Abouelmagd, Ivelin Koev, Ravi Chotalia, Abdulmalik Koya, Hany Eldeeb, Hisham Ahamed, Harshil Dhutia, Riyaz Somani, G Andre Ng, Mokhtar Ibrahim, 127 A comparative analysis of conduction system pacing and conventional pacing in patients undergoing atrioventricular node ablation: a systematic review and meta-analysis Free,BMJ Publishing Group Ltd and British Cardiovascular Society,2024.

Publisher : BMJ Publishing Group Ltd and British Cardiovascular Society

Year : 2024

Phenotypic expression, genotypic profiling and clinical outcomes of infantile hypertrophic cardiomyopathy: a retrospective study

Cite this Research Publication : Hisham Ahamed, Shruti Varghese, Georg Gutajahr, Balu Vaidyanathan, Mahesh Kappanayil, Navaneetha Sasikumar, Shine Kumar, Aparna Hari, Malavika Krishnakumar, Raman Krishna Kumar, Phenotypic expression, genotypic profiling and clinical outcomes of infantile hypertrophic cardiomyopathy: a retrospective study, Archives of Disease in Childhood,2024.

Publisher : BMJ Publishing

Year : 2023

Genotypic and Phenotypic Guided Antiarrhythmic Drug Management of Multifocal Premature Ventricular Contractions

Cite this Research Publication : Arun Gopi, Hisham Ahamed, Bridget Lee, Arun Mahtani, Jamarcus Brider, Kirollos Gabrah, Brandon Doty, Feross Al-Hindi, Devi Nair, Genotypic and Phenotypic Guided Antiarrhythmic Drug Management of Multifocal Premature Ventricular Contractions, Circulation,2023.

Publisher : Lippincott Williams & Wilkins

Year : 2022

Mutation of the MYL3 gene in a patient with mid-ventricular obstructive hypertrophic cardiomyopathy

Cite this Research Publication : Akash Mavilakandy, Hisham Ahamed, Mutation of the MYL3 gene in a patient with mid-ventricular obstructive hypertrophic cardiomyopathy, BMJ Case Reports CP,2022.

Year : 2022

Association of LpPLA2 with coronary artery disease a hospital-based case control study

Cite this Research Publication : Jaideep C Menon Rajesh Thachathodiyil, Anugrah Nair, Rajiv Chandrasekhar, Natarajan Kumaraswamy, Vijayakumar Maniyal, Praveen G Pai, Navine Mathew, Harikrishnan S Madhavankutty, Saritha Sekhar, Hisham Ahmed, Jofy Paul, Riji Thomas, Aneesa Ayoob, Chandrasekhar Janakiram, Association of LpPLA2 with coronary artery disease a hospital-based case control study, International Journal of Clinical Biochemistry and Research,2022.

Year : 2022

Desmin Myopathy—A Masquerader of Infantile-Onset Pompe Disease

Cite this Research Publication : Abdul Rauf, Hisham Ahamed, Mohamed Shanil, Sapna Sandal, Desmin Myopathy—A Masquerader of Infantile-Onset Pompe Disease, Indian Journal of Pediatrics,2022.

Publisher : Springer

Year : 2022

Light Chain(AL) Cardiac Amyloidosis: A Real World Data on Therapy and Outcomes

Cite this Research Publication : Sandeep Abhijit Pattnaik, Hisham Ahamed, Chitresh Yadav, Manoj Unni, Varsha K Rajeev, Vasundhara Raina, Nikhil Krishna Haridas, Rema Ganapathy, Mobin Paul, Ullas Mony, Neeraj Sidharthan, Damodhar Reddy Gouni, Rashmi Suresh Yawalkar, Shreya Gopal Agrawal, Gohul Gopi Jalajakumari; "Light Chain(AL) Cardiac Amyloidosis: A Real World Data on Therapy and Outcomes," Blood 2022; 140 (Supplement 1): 12578–12580. doi: https://doi.org/10.1182/blood-2022-169597

Publisher : Blood, ASH Publications

Year : 2022

Cardiac tamponade as a presentation of COVID-19 after cardiac surgery

Cite this Research Publication : Gopal K, Ahamed H, Jose R, Varma PK. "Cardiac tamponade as a presentation of COVID-19 after cardiac surgery," Indian J Thorac Cardiovasc Surg. 2022;38(2):191-194. doi:10.1007/s12055-021-01270-6

Publisher : Indian Journal of Thoracic and Cardiovascular Surgery

Year : 2022

Posterior mitral leaflet plication with extended septal myectomy for hypertrophic obstructive cardiomyopathy

Cite this Research Publication : Dr. Praveen Varma, Kirun Gopal, Ahamed, H., and Vanga, S. Babu, “Posterior mitral leaflet plication with extended septal myectomy for hypertrophic obstructive cardiomyopathy”, Indian J Thorac Cardiovasc Surg (2021). https://doi.org/10.1007/s12055-021-01213-1

Year : 2021

Derivation and validation of a novel prognostic model for patients with light chain (AL) cardiac amyloidosis

Cite this Research Publication : M Subramanian, H Ahamed, N Mathew, A Aribandi, C Narasimhan, Derivation and validation of a novel prognostic model for patients with light chain (AL) cardiac amyloidosis,European Journal of Heart Failure, 2021.

Year : 2021

Familial left ventricular noncompaction cardiomyopathy due to a novel mutation in the MYH 7 gene

Cite this Research Publication : Sujata S Alawani, Abraham Paul, Mani Ram Krishna, Hisham Ahamed, Familial left ventricular noncompaction cardiomyopathy due to a novel mutation in the MYH 7 gene, Annals of Pediatric Cardiology,2021.

Year : 2021

Do alternative approaches work in surgical septal myectomy?

Cite this Research Publication : Varma PK, Krishna N, Jose R, Gopal K, Ahamed H., "Do alternative approaches work in surgical septal myectomy?," Asian Cardiovascular and Thoracic Annals, 2021 0(0) 1–8. https://doi.org/10.1177/02184923211025396

Publisher : Asian Cardiovascular and Thoracic Annals

Year : 2021

Bleeding complications after dual antiplatelet therapy with ticagrelor versus dual antiplatelet therapy with clopidogrel—a propensity-matched comparative study of two antiplatelet regimes in off-pump coronary artery bypass grafting

Cite this Research Publication : 14. Varma PK, Ahmed H, Krishna N, et al. Bleeding complications after dual antiplatelet therapy with ticagrelor versus dual antiplatelet therapy with clopidogrel-a propensity-matched comparative study of two antiplatelet regimes in off-pump coronary artery bypass grafting. Indian Journal of Thoracic and Cardiovascular Surgery. 2021;37(1):27-37. doi:10.1007/s12055-020-01052-6

Publisher : Indian Journal of Thoracic and Cardiovascular Surgery

Year : 2020

Abnormal mitral valve apparatus is not an indication for mitral valve replacement in hypertrophic obstructive cardiomyopathy

Cite this Research Publication : Dr. Praveen Varma and Ahamed, H., “Abnormal mitral valve apparatus is not an indication for mitral valve replacement in hypertrophic obstructive cardiomyopathy”, Annals of Cardiac Anaesthesia, vol. 23, no. 2, pp. 246-247, 2020.

Publisher : Annals of Cardiac Anaesthesia

Year : 2019

Missense Mutations in the FLNC Gene Causing Familial Restrictive Cardiomyopathy

Cite this Research Publication : Dr. Hisham Ahamed and Subramanian, M., “Letter by Ahamed and Subramanian Regarding Article "Missense Mutations in the FLNC Gene Causing Familial Restrictive Cardiomyopathy".”, Circ Genom Precis Med, vol. 12, no. 7, p. e002587, 2019.

Publisher : Circ Genom Precis Med,

Year : 2019

Arrhythmogenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome

Cite this Research Publication : M. Subramanian, Peravali, S., Dr. Hisham Ahamed, and Navin Mathew, “Arrhythmogenic right ventricular cardiomyopathy and sick sinus syndrome : a potential overlap syndrome”, European Heart Journal - Cardiovascular Imaging , vol. 20, Suppliment 2, p. ii53, 2019.


Publisher : European Heart Journal - Cardiovascular Imaging

Year : 2019

Letter by Ahamed and Subramanian Regarding Article "Missense Mutations in the FLNC Gene Causing Familial Restrictive Cardiomyopathy".

Cite this Research Publication : Dr. Hisham Ahamed and Subramanian, M., “Letter by Ahamed and Subramanian Regarding Article "Missense Mutations in the FLNC Gene Causing Familial Restrictive Cardiomyopathy".”, Circ Genom Precis Med, vol. 12, no. 7, p. e002587, 2019.

Publisher : Circ Genom Precis Med

Year : 2018

Posterior mitral leaflet plication for hypertrophic obstructive cardiomyopathy.

Cite this Research Publication : Dr. Praveen Varma, Krishna, N., Dr. Hisham Ahamed, and Madassery, S., “Posterior mitral leaflet plication for hypertrophic obstructive cardiomyopathy.”, Asian Cardiovascular and Thoracic Annals, vol. 26, no. 5, pp. 400-403, 2018.

Publisher : Asian Cardiovascular and Thoracic Annals .

Year : 2018

Left Atrial Approach to Septal Myectomy: Word of Caution.

Cite this Research Publication : Dr. Praveen Varma and Dr. Hisham Ahamed, “Left Atrial Approach to Septal Myectomy: Word of Caution.”, Annals of Thoracic Surgery, vol. 106, no. 5, pp. 1591-1592, 2018.


Publisher : Annals of Thoracic Surgery

Year : 2017

Familial restrictive cardiomyopathy: A novel troponin mutation

Cite this Research Publication : M. Subramanian, Dr. Hisham Ahamed, and Mathew, N., “Familial restrictive cardiomyopathy: A novel troponin mutation”, Indian Heart Journal, vol. 69, Suppliment 2, pp. S87 - S88, 2017.

Publisher : Indian Heart Journal

Year : 2017

1025PIndependent predictors of one year mortality in patients with primary systemic immunoglobulin light chain cardiac amyloidosis

Cite this Research Publication : S. V., Subramaniam, M., Shanmugam, A., Philip, A., Susan, A., Prabhu, R., Unni, M., Sidharthan, N., Jose, W., V., S. N., Dr. Hisham Ahamed, Mathew, N., and Keechilat, P., “1025PIndependent predictors of one year mortality in patients with primary systemic immunoglobulin light chain cardiac amyloidosis”, Annals of Oncology, vol. 28, 2017.

Publisher : Annals of Oncology

Conference Proceedings

Year : 2023

Detection of Hypertrophic Cardiomyopathy from Echocardiography: A Survey of Current Approaches

Cite this Research Publication : Abdullah A Muhamed, MR Jivthesh, MR Gaushik, Nagesh Subbanna, Hisham Ahamed, Detection of Hypertrophic Cardiomyopathy from Echocardiography: A Survey of Current Approaches, 2023 3rd International Conference on Pervasive Computing and Social Networking (ICPCSN),2023.

Publisher : IEEE

Year : 2023

Segmentation of heart wall muscles and detection of hypertrophic cardiomyopathy from 2D echo images using U- Nets

Cite this Research Publication : A Aiswarya, Hisham Ahamed, Nagesh Subbanna, Segmentation of heart wall muscles and detection of hypertrophic cardiomyopathy from 2D echo images using U- Nets, 2023 14th International Conference on Computing Communication and Networking Technologies (ICCCNT),2023.

Publisher : IEEE

Book Chapter

Year : 2018

Hypertrophic cardiomyopathy

Cite this Research Publication : Dr. Hisham Ahamed, J.Maron, D. Barry, and S.Maron, D. Martin, “Hypertrophic Cardiomyopathy”, in Tandon's Textbook of Cardiology , Wolters Kluwer India Pvt. Ltd., 2018.

Publisher : Tandon's Textbook of Cardiology , Wolters Kluwer India Pvt. Ltd.

Area of Expertise
  • Hypertrophic Cardiomyopathy
  •  Cardiovascular genetics
  • Cardiac Amyloidosis
  • Advanced Cardiac Imaging – Cardiac MRI with multiparametric mapping
  • Interventional Cardiology
  • Inherited Cardiovascular Disease
Education
  • DM Cardiology Amrita Institute of Medical Sciences and Research, Kochi Dissertation: “Incidence of Sudden Cardiac Death in A Post MI Cohort in a tertiary care hospital” August 2012
  • MD Internal MedicineSri Ramachandra University and Hospital, Chennai Thesis: “Prevalence of Secondary Bacterial Infection in Newly Diagnosed Pulmonary Tuberculosis” May 2008
  • MBBS J.S.S Medical College, Mysore. April 2003
  • Fellowship in Interventional CardiologyAmrita Institute of Medical Sciences and Research August 2013
Work Experience
  • 2020-PresentAssociate Professor in Cardiology,Amrita Hospital, Kochi
  • 2015-2020Assistant Professor in Cardiology, Amrita Hospital, Kochi
Awards and Achievements
  • Awarded the Gold Medal for “The Best Outgoing Candidate – Academic Performance” from Sri Ramachandra University and Hospital
  • Awarded the best-case presentation for ” A case of reactive thrombocytosis ” during monthly hospital multi-speciality meet ( 2005 ) Amrita Hospital, Kochi
  • Awarded the Gold Medal for “The best academic performance in DM Cardiology” during the university examinations conducted in 2012
  • Amrita Hypertrophic Cardiomyopathy Registry and Clinic
    Project Lead, Amrita Hypertrophic Cardiomyopathy Registry and Clinic
    Founded the Amrita Hypertrophic Cardiomyopathy Registry and Clinic in 2013. This was the first comprehensive center of excellence for HCM care in India. This was established with mentorship under Dr Barry.J.Maron and Dr Martin.S. Maron from Tuft’s HCM Center, Boston.
    (References : Importance and feasibility of creating hypertrophic cardiomyopathy centers in developing countries: the experience in India. Maron BJ. Am J Cardiol. 2015 Jul 15;116(2):332-4. doi: 10.1016/j.amjcard.2015.04.027. Epub 2015 Apr 18.)
  • Hypertrophic Cardiomyopathy Summit VI, Boston, USA
    Speaker : ” HCM in the Developing World ”
    Was an invited speaker : International Summit VI: Hypertrophic cardiomyopathy – A Contemporary and Treatable Genetic Disease: Diagnosis, Heart Failure Management, and Prevention of Sudden Death, held in Boston, MA, October 27-29, 2017, at the Seaport Hotel & World Trade Center. Spoke on “HCM in the developing world”and was the only invited speaker from the South Asian region.
  • Chapter Author : “Hypertrophic Cardiomyopathy” in Tandon’s Textbook of Cardiology (2018)
    Chapter Author : “Hypertrophic Cardiomyopathy” in Tandon’s Textbook of Cardiology (2018)
    Co-authors : Dr Barry.J.Maron and Dr Martin.S.Maron
  • National Cardio-Oncology Summit, 2017
    • Co-Founded India’s first National Cardio- Oncology Society in 2017 (Secretary of the NCOS)
    • Co-Founded India’s first National Cardio-Oncology Summit in 2017 (Ramada Hotel, 2017) under the auspices of Canadian Cardio Oncology Society and International Cardio-Oncology Society
    • Co-Director of the very first dedicated Cardio-Oncology service at Amrita Institute of Medical Sciences and Research, Kochi
    • Organizing Secretary of India’s first National Cardio-Oncology Summit at Ramada Hotel and Resorts, 2017 under the auspices of Canadian Cardio Oncology Society and International Cardio-Oncology Society
  • ICCG : Brisbane, Australia 2018
    International Clinical Cardiovascular Genetics , Brisbane (2018)
    Presented 3 cardiovascular genomics papers at the ICCG, 2018 held at Brisbane:

    • Clinical outcome and phenotypic expression of PRKAG2 Cardiomyopathy
    • Familial Non- Syndromic Thoracic Aortic Dissection and Thoracic Aneurysm with an MYH 11 mutation
    • Clinical Profile of a Large Family with Familial HCM and Sudden Cardiac Death with an Alpha- Tropomyosin mutation
  • Annual Kerala State Echocardiography Meet, 2017
    Organizing secretary of the Kerala Chapter of the Annual Indian Academy of Echocardiography Meet in 2017 (Ramada Hotel, Kochi)
  • Annual Indian Academy of Echocardiography (2016) at Madurai
    Best Case presentation – Award session
    Won the award for best case presentation at Annual Indian Academy of Echocardiography meeting at Madurai ( 2016 ) for “Carcinoid Heart Disease : Flushing out the diagnosis”
  • Case Presentation : Awards Session (CSI HFCON 2019)
    PRKAG2 Cardiomyopathy : A South Asian Cohort
    Presented the paper : PRKAG2 Cardiomyopathy : A South Asian Cohort at National CSI HFCON, 2019 during the Awards Session.
  • Amrita Cardiovascular Genomics Service, 2015
    Founded the Amrita Cardiovascular Genomics Service, the first dedicated cardiovascular genomics service in the region. The service addresses all aspects of evaluation of inherited cardiovascular disease of patients and family screening along with advanced next generation sequencing and genetic counseling.
  • Amrita Amyloid Center, 2023
    Organised the Amrita Amyloid Summit, India’s first Amyloid summit, with Dr Ron Witteles (Director, Stanford Amyloid Center). Formally established the Amrita Amyloid Center, the first Amyloid center of excellence in the region.
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