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Dr. Kaladhar Kamalasanan

Associate Professor, Department of Pharmaceutics, School of Pharmacy, Kochi

Qualification: B. Pharm., M. Pharm., Ph.D
kaladhar22654@aims.amrita.edu
Curriculum Vitae
Research Interest: Biomaterials, Biophysics, Cardiology, Materials Science, Nanotechnology, Wound Healing

Bio Publications Education & Work Experience Research Awards Talks Student Guide In the Media
Bio

Dr. Kaladhar Kamalasanan currently serves as Associate Professor at the Department of Pharmaceutics, Amrita School of Pharmacy. He joined as Assistant Professor in the Department of Pharmaceutics, Amrita School of Pharmacy in September 2015. He has last served as Fellow Scientist –D at Sree Chitra Tirunal Institute for Medical Sciences and Technology, India and is currently consulting for various organizations nationally and internationally.

He has more than three years of post-doctoral research experience in the USA from one of the premier research groups in immunotherapeutics and drug delivery, Mc Gowan Institute for Regenerative Medicine; Department of Chemical Engineering, Bioengineering & Immunology, University of Pittsburgh, USA as well as he was a visiting scholar to Phillipps University, Marburg in Germany for 2 years.

He has completed Ph. D. in Biomedical Engineering (Biosurface Modification), Biomedical Technology Division, Sree Chitra Tirunal Institute for Medical Sciences and Technology. He has also done his M. Pharm. at Annamalai University, Tamil Nadu and Bachelor of Pharmacy at Dr. MGR University, Tamil Nadu.

He has developed products filed several national and international patents, bagged several awards and has several research articles, book chapters and conference proceedings. He also actively participated in various professional society activities.

Dr. Kaladhar has nearly 2 decades of research, technology development and academic experience in translational medicine. This is by exploring fully funded research at SCTIMST (institute of national importance), Thiruvananthapuram, Kerala, India, University of Pittsburgh, USA, Phillips University Marburg, Germany and Amrita School of Pharmacy, Kochi Kerala, India.

Lead to platform drug delivery systems; commercialization of oral delayed-release capsules, and multi-drug formulations. Work involves, TRL5 techno demos (Science driven) of class III medical devices and TRL 6-9 (Science, engineering, clinically driven) ongoing projects. Introduced the area of “Controlled Release Nanomedicines (CRNMs)” and “Prophynostics” and working towards expanding these areas for applications in personalized medicine.  Written Biomaterials Chapter in Vision 2035 document by TIFAC, DST India. Several publications in journals like Angewandte, Langmuir and JCR as 1st or corresponding author.

Nearly 10 Indian provisional patents and 1 US patent granted. Written H2020 consortium project on TB vaccine with 9 institutes internationally. Initiated and written CADDS and FADDS (currently CAF) at SCTIMST with Prof. Sharma CP. Now supporting Research-Industry Network and teaching/guiding at pharmacy school and consulting for Pharma/ biomedical companies and research labs. Attracted funds worth (10Cr rupees and submitted projects worth 55Cr Rs. from period of Ph.D. student to tenured track). Invented technologies later introduced into the market includes MicroDox DR Capsules, Stem cell technologies, surface coatings, advanced multi-drug eye drops, COVID medicine. 

Profile

  • An academic with more than 20 years of research/academic experience (Fully funded research in advanced research institutes such as SCTIMST (institute of national importance), Phillips University Marburg Germany, University of Pittsburgh, USA) and 6 years of teaching and 8 yers consulting experience at present actively networking in research, teaching, clinical, industrial and policy aspects of pharmaceutical therapeutics and medical devices.
  • Expertise in design and development of biomaterial and pharmaceutical technology development to address unmet clinical needs combining in silico, ex vivo, in vitro and in vivo studies.
  • Currently consulting for organizations nationally and internationally with a mission of extending the borders of “biomaterial-based technology development and transfer”. 
  • From July 1, 2021, onwards as Associate Professor and consultant at Amrita School of Pharmacy (ASP) in connection with Amrita Center for Nanoscience and Molecular Medicine (ACNMM).
  • From September 7, 2015, onwards served as an Assistant professor and consultant at Amrita School of Pharmacy (ASP) in connection with Amrita Center for Nanoscience and Molecular Medicine (ACNMM).
  • From February 22, 2012- to February 22, 2015, was leading translational research in immunotherapeutics and nanomedicine at the capacity of adhoc faculty position as Fellow scientist – D (Chitra High Value Fellow) at Sree Chitra Tirunal Institute for Medical Science and Technology, India, (an institute of national importance by federal law). 
  • From January 1, 2009- February 7, 2012, working as a Postdoctoral Associate in USA from one of the premier research groups in immunotherapeutics and drug delivery for 3-4 years as well as in Germany as visiting scholar in material science, drug delivery, nanotechnology and surface coatings.
  • Experience in years in a nutshell (2021): Biomaterial/ translational medicine Research- 20, Consulting- 8, Teaching- 6, Industry-5, Entrepreneurial – 6. 
  • Area of working: Controlled Release Nanomedicines (CRNMs) (2015), Prophynostics (2020),  Immunotherapeutics (2012) , Biomaterials (2001), Medical devices, Tissue engineering and Regenerative medicine, Drug Delivery (1999),
Publications

Journal Article

Year : 2021

Section Review Articles Design of a Combination Model of an Abdominal Tourniquet, a 3D Printed Drug Delivering Endotracheal Tube and a Transdermal Patch for Improving CPR Efficiency at In hospital Conditions

Cite this Research Publication : Kaladhar, K., Abhi, C., Gokul, T., Baby, A., Sreejith, T., Design of a combination model of an abdominal tourniquet, a 3D printed drug delivering endotracheal tube and a transdermal patch for improving cpr efficiency at in hospital conditions, Trends in Biomaterials and Artificial Organs, 2021, 35(3), pp. 283-286

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2021

Drug delivery to optimize angiogenesis imbalance in keloid: A review

Cite this Research Publication : Kumar, A.S., Kamalasanan, K. Drug delivery to optimize angiogenesis imbalance in keloid: A review, Journal of Controlled Release, 2021, 329, pp. 1066-1076. DOI: https://doi.org/10.1016/j.jconrel.2020.10.035

Publisher : Journal of Controlled Release

Year : 2020

Zero-dimensional Nanotubes as Nano-devices to Dismantle COVID-19: Possibilities of Advanced Coatings,” Nanoinstant Vaccines” and” Prophynostics”

Cite this Research Publication : K. Kamalasanan, “Zero-dimensional Nanotubes as Nano-devices to Dismantle COVID-19: Possibilities of Advanced Coatings," Nanoinstant Vaccines" and" Prophynostics".”, Trends in Biomaterials & Artificial Organs, vol. 34, pp. 38-43, 2020.

Publisher : Trends in Biomaterials & Artificial Organs

Year : 2020

Biomimetic Conjoining Pathways for COVID-19 Nanomedicine Drug Discovery and Medical Devices: Prophylactic Medicines as Alternative for Vaccines

Cite this Research Publication : K. Kamalasanan, “Biomimetic Conjoining Pathways for COVID-19 Nanomedicine Drug Discovery and Medical Devices: Prophylactic Medicines as Alternative for Vaccines”, Trends in Biomaterials & Artificial Organs, vol. 34, no. 4, pp. 73-74., 2020.

Publisher : Trends in Biomaterials & Artificial Organs

Year : 2020

Zero-dimensional nanotubes as nano-devices to dismantle COVID-19: Possibilities of advanced coatings, “nano-instant vaccines” and “prophynostics”

Cite this Research Publication :
Dr. Kaladhar Kamalasanan, “Zero-dimensional nanotubes as nano-devices to dismantle COVID-19: Possibilities of advanced coatings, "nano-instant vaccines" and "prophynostics"”, Trends in Biomaterials and Artificial Organs, vol. 34(S2), pp. 38-43, 2020.

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2020

Biomimetic conjoining pathways for COVID-19 drug discovery, nanomedicine and medical devices: Prophylactic medicines as alternative for vaccines

Cite this Research Publication : Dr. Kaladhar Kamalasanan, “Biomimetic conjoining pathways for COVID-19 drug discovery, nanomedicine and medical devices: Prophylactic medicines as alternative for vaccines”, Trends in Biomaterials and Artificial Organs, vol. 34, no. 3, pp. 73-74, 2020

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2020

Controlled drug delivery for alopecia: A review

Cite this Research Publication : Dr. Kaladhar Kamalasanan and S, S., “Controlled drug delivery for alopecia: A review”, Journal of Controlled Release, vol. 325, pp. 84-99, 2020

Publisher : Journal of Controlled Release

Year : 2020

Drug Delivery in New Decade of 2020 Onwards: Considerations for Designing Diffusion Based Drug Delivery Devices

Cite this Research Publication : Dr. Kaladhar Kamalasanan, “Drug Delivery in New Decade of 2020 Onwards: Considerations for Designing Diffusion Based Drug Delivery Devices”, Trends in Biomaterials and Artificial Organs, vol. 34, no. 3, pp. 73-74, 2020

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2020

Zero-dimensional nanotubes as nano-devices to dismantle COVID-19: Possibilities of advanced coatings, “nano-instant vaccines” and “prophynostics

Cite this Research Publication :
Dr. Kaladhar Kamalasanan, “Zero-dimensional nanotubes as nano-devices to dismantle COVID-19: Possibilities of advanced coatings, "nano-instant vaccines" and "prophynostics"”, Trends in Biomaterials and Artificial Organs, vol. 34(S2), pp. 38-43, 2020.

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2019

Infection control in lower limb ulcers for wound healing current status and future perspectives (Under review)International journal of nanomedicine

Cite this Research Publication : Dr. Kaladhar Kamalasanan and B., B., “Infection control in lower limb ulcers for wound healing current status and future perspectives (Under review)”, International journal of nanomedicine, 2019.

Publisher : International journal of nanomedicine

Year : 2019

Tuberculosis control current status and future prospectives for developing nanomedicine strategies (Under review)

Cite this Research Publication : Dr. Kaladhar Kamalasanan and T., T., “Tuberculosis control current status and future prospectives for developing nanomedicine strategies (Under review)”, Journal of Controlled Resease, 2019.

Publisher : Journal of Controlled Resease

Year : 2019

Formulation of different polymer coated spherules from granules

Cite this Research Publication : V. K.V., Hansan, M., Madhu, K., Dr. Kaladhar Kamalasanan, and Renju Radhakrishnan, “Formulation of different polymer coated spherules from granules”, Journal of Pharmaceutical Sciences and Research, vol. 11, no. 4, pp. 1633-1637, 2019

Publisher : Journal of Pharmaceutical Sciences and Research

Year : 2019

Infection control in lower limb ulcers for wound healing current status and future perspectives

Cite this Research Publication : Dr. Kaladhar Kamalasanan and B., B., “Infection control in lower limb ulcers for wound healing current status and future perspectives (Under review)”, International journal of nanomedicine, 2019.

Publisher : International journal of nanomedicine

Year : 2019

Prophylaxis using estradiol nano-medicine based occular insert suppresses allergic conjunctivitis in rat model: A “tradition-mimetic” approach (Under Review)

Cite this Research Publication : Dr. Kaladhar Kamalasanan and D., D., “Prophylaxis using estradiol nano-medicine based occular insert suppresses allergic conjunctivitis in rat model: A “tradition-mimetic” approach (Under Review)”, Colloids and Surfaces B: Biointerfaces, 2019.

Publisher : Colloids and Surfaces B: Biointerfaces

Year : 2019

Novel Aspirin Controlled Release Nanomedicine Suppresses Platelet Aggregation: Implications for Extending the Golden Hour in Stroke (Under review)

Cite this Research Publication : Dr. Kaladhar Kamalasanan, R., J., and Dr. Sabitha M., “Novel aspirin controlled release nanomedicine suppresses platelet aggregation: implications for extending the golden hour in stroke (Under review)”, Pharmaceutical Research, 2019.

Publisher : Pharmaceutical Research

Year : 2018

Formulation of a novel immediate release heterolithic buccal patch of aspirin

Cite this Research Publication :
J. Rajeev, Mukundan, S., Raj, K. S. Bimal, Dhanaja, V. P., Subburaj, T., and Dr. Kaladhar Kamalasanan, “Formulation of a novel immediate release heterolithic buccal patch of aspirin”, Journal of Pharmaceutical Sciences and Research, vol. 10, no. 8, pp. 2079-2083, 2018

Publisher : Pharmainfo Publications

Year : 2018

Magnesium stearate is an incompatible excipient for aspirin in wet granulation producing non-linear degradation

Cite this Research Publication :
D. D’cruz, Ajith, A., Subburaj, T., and Dr. Kaladhar Kamalasanan, “Magnesium stearate is an incompatible excipient for aspirin in wet granulation producing non-linear degradation”, Journal of Pharmaceutical Sciences and Research (JPSR) , vol. 10, no. 2, pp. 240-242, 2018

Publisher : Journal of Pharmaceutical Sciences and Research

Year : 2017

Early detection of epileptic siezures

Cite this Research Publication : S. K. Aiswari, Kavya, S. G., Thomas, K., and Dr. Kaladhar Kamalasanan, “Early detection of epileptic siezures”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India., 2017.

Publisher : Research Day, Amrita School of Pharmacy

Year : 2017

FABLE” First aids (FAs) for Blood Loss in Emergency-Campaign for Rural India Exploring Pharmacists

Cite this Research Publication : Dr. Kaladhar Kamalasanan, “"FABLE” First aids (FAs) for Blood Loss in Emergency-Campaign for Rural India Exploring Pharmacists”, Trends in Biomaterials and Artificial Organs , vol. 31, no. 1, pp. 33-40, 2017

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2017

Affordable Technologies to Stop Bleeding from Haemorrhage: New Role of Pharmacists in its R&D and Rational use in Rural India

Cite this Research Publication : J. Konikkara, Antony, A., Renju Radhakrishnan, Hanssen, M., Nair, A. J., Radhakrishnan, R., and Dr. Kaladhar Kamalasanan, “Affordable Technologies to Stop Bleeding from Haemorrhage: New Role of Pharmacists in its R&D and Rational use in Rural India”, International Journal of Pharmaceutical Sciences Review and Research, vol. 42, no. 2, pp. 194-200, 2017

Publisher : International Journal of Pharmaceutical Sciences Review and Research

Year : 2017

Nanomedicine for prostate cancer using nanoemulsion: A review.

Cite this Research Publication : A. Sasikumar and Dr. Kaladhar Kamalasanan, “Nanomedicine for prostate cancer using nanoemulsion: A review.”, Journal of Controlled Release, vol. 260, pp. 111-123, 2017.

Publisher : Journal of Control Release

Year : 2017

Early detection of seizures in epilepsy using point of care (POC) systems

Cite this Research Publication : A. S. Kumar, Kuruvila, T., Kavya, S. G., Radhakrishnan, R., Nair, A. J., and Dr. Kaladhar Kamalasanan, “Early detection of seizures in epilepsy using point of care (POC) systems”, Journal of Pharmaceutical Sciences and Research, vol. 9, no. 3, pp. 302-306, 2017

Publisher : Journal of Pharmaceutical Sciences and Research

Year : 2017

Current trend in drug delivery considerations for subcutaneous insulin depots to treat diabetes

Cite this Research Publication : J. PV, Shantikumar V Nair, and Dr. Kaladhar Kamalasanan, “Current trend in drug delivery considerations for subcutaneous insulin depots to treat diabetes”, Colloids and Surfaces B: Biointerfaces, vol. 153, pp. 123-131, 2017

Publisher : Colloids and Surfaces B: Biointerfaces,

Year : 2017

Affordable Technologies to Stop Bleeding from Haemorrhage: New Role of Pharmacists in its R&D and Rational use in Rural India

Cite this Research Publication : J. Konikkara, Antony, A., Renju Radhakrishnan, Hanssen, M., Nair, A. J., Radhakrishnan, R., and Dr. Kaladhar Kamalasanan, “Affordable Technologies to Stop Bleeding from Haemorrhage: New Role of Pharmacists in its R&D and Rational use in Rural India”, International Journal of Pharmaceutical Sciences Review and Research, vol. 42, no. 2, pp. 194-200, 2017.

Publisher : International Journal of Pharmaceutical Sciences Review and Research

Year : 2016

Affordable Medicines Exploring Organ Printing using “Make in India” Campaign

Cite this Research Publication : Dr. Kaladhar Kamalasanan, “Affordable Medicines Exploring Organ Printing using “Make in India” Campaign”, Trends in Biomaterials and Artificial Organs, vol. 30, no. 2, pp. 161–162, 2016.

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2015

Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response.

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Renz, H., and Sharma, C. P., “Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response.”, Colloids Surf B Biointerfaces, vol. 128, pp. 8-16, 2015.

Publisher : Colloids Surf B Biointerfaces, Volume 128, p.8-16 (2015)

Year : 2015

Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Renz, H., and Sharma, C. P., “Nano-anisotropic surface coating based on drug immobilized pendant polymer to suppress macrophage adhesion response.”, Colloids Surf B Biointerfaces, vol. 128, pp. 8-16, 2015

Publisher : Colloids Surf B Biointerfaces

Year : 2014

Supramolecular curcumin-barium prodrugs for formulating with ceramic particles.

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Anupriya,, Deepa, M. K., and Sharma, C. P., “Supramolecular curcumin-barium prodrugs for formulating with ceramic particles.”, Colloids Surf B Biointerfaces, vol. 122, pp. 301-308, 2014.

Publisher : Colloids Surf B Biointerfaces, Volume 122, p.301-308

Year : 2014

Anisotropic Surface Coatings Controls Drug Delivery From Reservoir Devices Similar to That of Erodible Systems

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Anisotropic Surface Coatings Controls Drug Delivery From Reservoir Devices Similar to That of Erodible Systems.”, Trends in Biomaterials & Artificial Organs, vol. 28, no. 4, pp. 176-181, 2014

Publisher : Trends in Biomaterials & Artificial Organs

Year : 2014

Supramolecular curcumin-barium prodrugs for formulating with ceramic particles

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Anupriya,, Deepa, M. K., and Sharma, C. P., “Supramolecular curcumin-barium prodrugs for formulating with ceramic particles.”, Colloids Surf B Biointerfaces, vol. 122, pp. 301-308, 2014.

Publisher : Colloids Surf B Biointerfaces

Year : 2014

Cell-mimetic coatings for immune spheres

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Renz, H., and Sharma, C. P., “Cell-mimetic coatings for immune spheres”, Colloids and Surfaces B: Biointerfaces, vol. 123, pp. 845–851, 2014.

Publisher : Elsevier

Year : 2014

Supramolecular curcumin–barium prodrugs for formulating with ceramic particles

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Anupriya,, Deepa, M. K., and Sharma, C. P., “Supramolecular curcumin–barium prodrugs for formulating with ceramic particles”, Colloids and Surfaces B: Biointerfaces, vol. 122, pp. 301 - 308, 2014.

Publisher : Elsevier B.V

Year : 2013

“Zero-Dimensional” Single-Walled Carbon Nanotubes

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Gottardi, R., Tan, S., Chen, Y., Godugu, B., Rothstein, S., Balazs, A. C., Star, A., and Little, S. R., ““Zero-Dimensional” Single-Walled Carbon Nanotubes”, Angewandte Chemie International Edition, vol. 52, no. 43, pp. 11308–11312, 2013

Publisher : Wiley Online Library

Year : 2011

Synthetic Cells with Ordered Protein Patches

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Little, S. R., “Synthetic Cells with Ordered Protein Patches”, Annual Meeting & Exposition (Poster). Orlando, Florida., 2011.

Publisher : Annual Meeting & Exposition

Year : 2011

Patchy, Anisotropic Microspheres with Soft Protein Islets

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Jhunjhunwala, S., Wu, J., Swanson, A., Gao, D., and Little, S. R., “Patchy, Anisotropic Microspheres with Soft Protein Islets”, Angewandte Chemie International Edition, vol. 50, no. 37, pp. 8706–8708, 2011.

Publisher : Wiley Online Library

Year : 2010

Self-assembly of quantum single walled carbon nanotubes

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Little, S. R., “Self-assembly of quantum single walled carbon nanotubes”, 10th AIChE Annual Meeting. Salt Lake City, USA., 2010.

Publisher : 10th AIChE Annual Meeting

Year : 2009

Preliminary studies on blood compatibility and Langmuir monolayer stability of gold nanoparticles stabilized through amino-PEG functionality

Cite this Research Publication : C. Durgadas, Dr. Kaladhar Kamalasanan, Divya, P., Sreenivasan, K., and Sharma, C., “Preliminary studies on blood compatibility and Langmuir monolayer stability of gold nanoparticles stabilized through amino-PEG functionality”, Trends Biomater. Artif. Organs, vol. 23, no. 2, pp. 86-92, 2009

Publisher : Trends Biomater. Artif. Organs

Year : 2009

Methods to prepare patchy microparticles

Cite this Research Publication : Dr. Kaladhar Kamalasanan and R. Steven, L., “Methods to prepare patchy microparticles”, U.S. Patent PCT/US2010/0517712009.

Year : 2007

Surface passivation and controlled ligand supplementation of cellular activation processes–strategies for bottom up synthesis of bioactive surfaces

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Surface passivation and controlled ligand supplementation of cellular activation processes–strategies for bottom up synthesis of bioactive surfaces”, Trends in Biomaterials and Artificial Organs, vol. 21, no. 1, pp. 29–62, 2007.

Publisher : Trends in Biomaterials and Artificial Organs

Year : 2006

Cell mimetic monolayer supported chitosan-haemocompatibility studies

Cite this Research Publication : S. Mathews, Dr. Kaladhar Kamalasanan, and Sharma, C. P., “Cell mimetic monolayer supported chitosan-haemocompatibility studies”, Journal of Biomedical Materials Research Part A, vol. 79, no. 1, pp. 147–152, 2006.

Publisher : Wiley Online Library

Year : 2006

Cell mimetic lateral stabilization of outer cell mimetic bilayer on polymer surfaces by peptide bonding and their blood compatibility

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Cell mimetic lateral stabilization of outer cell mimetic bilayer on polymer surfaces by peptide bonding and their blood compatibility”, Journal of Biomedical Materials Research Part A, vol. 79, no. 1, pp. 23–35, 2006

Publisher : Wiley Online Library

Year : 2006

Studies in Formulation of Delayed Release Capsules of Doxycycline Hyclate

Cite this Research Publication : S. C. Basak, Dr. Kaladhar Kamalasanan, and Subburaj, T., “Studies in Formulation of Delayed Release Capsules of Doxycycline Hyclate”, ACTA Pharmaceutica Sciencia, vol. 48, no. 2, pp. 121- 128, 2006

Publisher : ACTA Pharmaceutica Sciencia

Year : 2004

Supported cell mimetic monolayers and their interaction with blood

Cite this Research Publication : K. Kaladhar and Sharma, C. P., “Supported cell mimetic monolayers and their interaction with blood”, Langmuir, vol. 20, no. 25, pp. 11115–11122, 2004.

Publisher : ACS Publications

Year : 2004

Doxycycline hyclate delayed release capsules with sodium starch glycolate as a pH-dependent pore forming agent

Cite this Research Publication : S. C. Basak, Dr. Kaladhar Kamalasanan, and Subburaj, T., “Doxycycline hyclate delayed release capsules with sodium starch glycolate as a pH-dependent pore forming agent”, Indian journal of pharmaceutical sciences, vol. 66, no. 5, pp. 704–707, 2004.

Publisher : MedKnow Publications and Media

Conference Proceedings

Year : 2018

Development of Aspirin Loaded Niosome

Cite this Research Publication : R. Jeevna and Dr. Kaladhar Kamalasanan, “Development of aspirin loaded niosome”, Biomet-2018, International Conference on Biomaterials, Bioengineering and Biotheranostics. VIT, Vellore, TN, India., 2018.

Publisher : Biomet-2018, International Conference on Biomaterials, Bioengineering and Biotheranostics, VIT, Vellore, TN, India.

Year : 2018

Floating Drug Delivery Sytems using Diclofenac sodium as a model drug

Cite this Research Publication : M. Krishnapriya and Dr. Kaladhar Kamalasanan, “Floating drug delivery sytems using diclofenac sodium as a model drug”, Biomet- 2018, International Conference on Biomaterials, Bioengineering and Biotheranostics. VIT, Vellore, TN, India, 2018.

Publisher : Biomet-2018, International Conference on Biomaterials, Bioengineering and Biotheranostics. VIT, Vellore, TN, India.

Year : 2012

Fabrication of Highly Ordered and Close Packed Colloidal Crystals From Large Microparticles

Cite this Research Publication : M. H. Lash, Dr. Kaladhar Kamalasanan, Mccarthy, J., and Little, S. R., “Fabrication of Highly Ordered and Close Packed Colloidal Crystals From Large Microparticles”, 12th AICHE Annual meeting. Pittsburgh, PA, USA., 2012.

Publisher : 12th AICHE Annual meeting

Year : 2002

Insulin Drug Delivery by Sublingual Route

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Insulin Drug Delivery by Sublingual Route”, MACRO 2002, International Seminar on Frontiers of Polymer Science and Engineering. IIT, Kharagpur, India., 2002.

Publisher : IIT, Kharagpur

Book Chapter

Year : 2018

Pharmaceutical perspectives of selection criteria and toxicity profiling of nanotheranostic agents

Cite this Research Publication : R. Radhakrishnan and Dr. Kaladhar Kamalasanan, “Pharmaceutical perspectives of selection criteria and toxicity profiling of nanotheranostic agents”, in Drug Delivery Nanosystems for Biomedical Applications, Elsevier, 2018, pp. 45–74.

Publisher : Drug Delivery Nanosystems for Biomedical Applications, Elsevier.

Year : 2011

Manipulation of biomaterial interface by biomimetic strategies: Possibilities of exploring stem cells

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Manipulation of biomaterial interface by biomimetic strategies: Possibilities of exploring stem cells”, in Stem Cell Technologies: Basics and Applications, Edited by Satish Totey, Kaushik D. Deb, McGrawHill, 2011, pp. 200-214.

Publisher : Stem Cell Technologies: Basics and Applications

Year : 2009

Supported Cell Mimetic Monolayers and their Blood Compatibility

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Supported Cell Mimetic Monolayers and their Blood Compatibility”, in Advanced Biomaterials: Fundamentals, Processing, and Applications, Edited by Bikramjit Basu Dhirendra S. Katti Ashok Kumar , Wiley Online Library, 2009, pp. 663–676

Publisher : Wiley Online Library

Year : 2009

Possibilities of Using Cord Blood for Improving the Biocompatibility of Implants

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Possibilities of Using Cord Blood for Improving the Biocompatibility of Implants”, in Frontiers of Cord Blood Science, P. Stubblefield and Bhattacharya, N., Eds. London: Springer London, 2009, pp. 319–330

Publisher : Springer London

Patents

Year : 2017

Globular protein derivative based reconstituted nanoparticle suspension for the controlled delivery of insulin in injections (Under Submission)

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Nair, S. V., “Globular protein derivative based reconstituted nanoparticle suspension for the controlled delivery of insulin in injections (Under Submission)”, 2017.

Publisher : (2017)

Year : 2014

Sublingual delivery of insulin

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Sublingual delivery of insulin”, 2014.

Year : 2013

Surface coatings for phenotype regulation of adherent cells

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Surface coatings for phenotype regulation of adherent cells”, U.S. Patent Indian Patent Appl. No. 160/CHE/20142013.

Publisher : U.S. Patent Indian Patent

Year : 2012

Novel amphiphilic nano-particle based thermoresponsive coatings on surfaces for tissue engineering applications

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Novel amphiphilic nano-particle based thermoresponsive coatings on surfaces for tissue engineering applications”, U.S. Patent Indian Patent Appl. No.: 17/CHE/20122012.

Publisher : Number Indian Patent Appl. No .: 17/CHE/2012

Year : 2012

Catheter assisted therapeutic delivery device

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Menon, R. N., Shenoy, S. J., Nair, R. R., and Sharma, C. P., “Catheter assisted therapeutic delivery device”, U.S. Patent Indian Patent Appl. No. 2138/CHE/20132012.

Publisher : Number Indian Patent Appl. No. 2138/CHE/2013

Year : 2012

Ceramic particles with fast and tunable degradation properties for antibacterial applications

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Jayalakshmi, A. C., Kumar, S. S. Pradeep, Vijayan, S., Varma, H. K., and Sharma, C. P., “Ceramic particles with fast and tunable degradation properties for antibacterial applications”, U.S. Patent Indian Patent Appl. No. 608/CHE/20132012.

Publisher : Number Indian Patent Appl. No. 608/CHE/2013

Year : 2012

Drug oligomer based nanoparticles with fast degrading properties

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Radhika, R., Kumar, S. S. Pradeep, Maya, A. N., and Sharma, C. P., “Drug oligomer based nanoparticles with fast degrading properties”, U.S. Patent Indian Patent Appl. No. 106/CHE/20132012.

Publisher : Number Indian Patent Appl. No. 106/CHE/2013

Year : 2009

Methods to prepare patchy microparticles

Cite this Research Publication : Dr. Kaladhar Kamalasanan and R. Steven, L., “Methods to prepare patchy microparticles”, U.S. Patent PCT/US2010/0517712009

Publisher : U.S. Patent PCT/US2010/0517712009.

Presentation

Year : 2019

Nanomedicine delivery from advanced tourniquet to stop hemorrhage from the lower limb extremities

Cite this Research Publication :
H. Megha, Juna, K., Alex, A., and Dr. Kaladhar Kamalasanan, “Nanomedicine delivery from advanced tourniquet to stop hemorrhage from the lower limb extremities”, Current Trends in Drug Development and Delivery Technology, Chiral, Nano and Herbal Technology (Best Poster Award). Nehru College of Pharmacy, Thrissur, Kerala, India, 2019.

Publisher : Nehru College of Pharmacy, Thrissur, Kerala, India.

Year : 2019

Nanomedicine to deliver antiplatelet agent from advanced tourniquet to suppress haematoma

Cite this Research Publication : H. Megha, Juna, K., Alex, A., and Dr. Kaladhar Kamalasanan, “Nanomedicine to deliver antiplatelet agent from advanced tourniquet to suppress haematoma”, International Conference on Clinical Pharmacy and Pharmaceutical Technology (Best Poster Award). Jamia Salafiya Pharmacy College, Malappuram, Kerala, 2019.

Publisher : Jamia Salafiya Pharmacy College, Malappuram, Kerala

Year : 2019

Nanomedicine for delivery of anti platelet agent from advanced tourniquet

Cite this Research Publication : K. Juna, Megha, H., Alex, A., and Dr. Kaladhar Kamalasanan, “Nanomedicine for delivery of anti platelet agent from advanced tourniquet”, Prime Pharma-Conclave 2019 (Best Poster Award). Prime College of Pharmacy, Palakkad, Kerala, India, 2019.

Publisher : Prime College of Pharmacy, Palakkad, Kerala, India.

Year : 2018

Development of medicated kajal based drug delivery system for the prophylaxis of allergic conjunctivitis

Cite this Research Publication : D. Dcruz and Dr. Kaladhar Kamalasanan, “Development of medicated kajal based drug delivery system for the prophylaxis of allergic conjunctivitis”, Biomet-2018, International Conference on Biomaterials, Bioengineering and Biotheranostics (Best Poster Award). VIT, Vellore, TN, India., 2018.

Publisher : Biomet-2018, International Conference on Biomaterials, Bioengineering and Biotheranostics (Best Poster Award), VIT, Vellore, TN, India.

Year : 2018

Advanced bandages to stop hemorrhage from lower limb extremities

Cite this Research Publication : K. Juna, Alex, A., Megha, H., and Dr. Kaladhar Kamalasanan, “Advanced bandages to stop hemorrhage from lower limb extremities”, International Conference on Biomaterials, Bioengineering and Biotheranostics (Best Poster Award- Sponsored by Springer - Nature). VIT, Vellore, TN, India, 2018

Publisher : International Conference on Biomaterials, Bioengineering and Biotheranostics (Best Poster Award- Sponsored by Springer - Nature), VIT, Vellore, TN, India.

Year : 2017

Controlled local delivery of insulin for accelerated wound healing

Cite this Research Publication : R. Rashmi, Renju, R., Nair, S. V., and Dr. Kaladhar Kamalasanan, “Controlled local delivery of insulin for accelerated wound healing”, 6th Asian Biomaterial Congress (Poster). Thiruvananthapuram, India, 2017.

Publisher : 6th Asian Biomaterial Congress

Year : 2017

Treatment strategies for tuberculosis resistaince

Cite this Research Publication : K. Thomas, Rehna, M., and Dr. Kaladhar Kamalasanan, “Treatment strategies for tuberculosis resistaince”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India., 2017.

Publisher : Amrita School of Pharmacy

Year : 2017

Advanced bandages to stop haemorrhage from the lower limb extremities

Cite this Research Publication : K. Juna, Alex, A., Megha, H., and Dr. Kaladhar Kamalasanan, “Advanced bandages to stop haemorrhage from the lower limb extremities”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India, 2017.

Publisher : Amrita School of Pharmacy

Year : 2017

Accelerated wound healing using nanosystems

Cite this Research Publication : R. Rashmi and Dr. Kaladhar Kamalasanan, “Accelerated wound healing using nanosystems”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India., 2017.

Publisher : Research Day, Amrita School of Pharmacy

Year : 2017

Pharmaceutical strategies for addressing cigarette smoking

Cite this Research Publication : S. G. Kavya, Aiswari, S. K., Thomas, K., and Dr. Kaladhar Kamalasanan, “Pharmaceutical strategies for addressing cigarette smoking”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India, 2017.

Publisher : Amrita School of Pharmacy

Year : 2017

Pharmacological strategies to address cataract

Cite this Research Publication : D. Delma and Dr. Kaladhar Kamalasanan, “Pharmacological strategies to address cataract”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India., 2017.

Publisher : Amrita School of Pharmacy

Year : 2017

Early detection of epileptic siezures

Cite this Research Publication : S. K. Aiswari, Kavya, S. G., Thomas, K., and Dr. Kaladhar Kamalasanan, “Early detection of epileptic siezures”, Research Day, Amrita School of Pharmacy (Poster). Kochi, Kerala, India., 2017.

Publisher : Research Day, Amrita School of Pharmacy

Year : 2017

Accelerated Bone Regeneration in Critical Calvarial Defect By Controlled Delivery of Insulin from Scaffold

Cite this Research Publication : A. J. Nair, Decruz, D., MB, N., SV, N., and Dr. Kaladhar Kamalasanan, “Accelerated Bone Regeneration in Critical Calvarial Defect By Controlled Delivery of Insulin from Scaffold”, 6th Asian Biomaterial Congress (Poster). Thiruvananthapuram, India., 2017.

Publisher : 6th Asian Biomaterial Congress

Year : 2017

Controlled growth factor delivery for bone regeneration

Cite this Research Publication : J. N. Athira and Dr. Kaladhar Kamalasanan, “Controlled growth factor delivery for bone regeneration”, Research Day, Amrita School of Pharmacy (Poster) . Kochi, Kerala, India., 2017.

Publisher : Research Day, Amrita School of Pharmacy

Year : 2015

Research-Industrial Networks (RIN)- Need of the hour in India

Cite this Research Publication : Dr. Kaladhar Kamalasanan, T B, S. Benjamin, and Sharma, C. P., “Research-Industrial Networks (RIN)- Need of the hour in India”, BITE-RM-2015, Indo-Australian Conf. on Biomaterials, Tissue Engg, Drug Delivery Systems, and Regenerative Medicine. 25th Annual Meeting of Society for Biomaterials and Artificial Organs India, 8th Annual Meeting of Society for Tissue Engg & Regenerative (Oral Presentation), 2015.

Publisher : BITE-RM

Year : 2010

Anisotropic Protein Patterned Microspheres

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Little, S. R., “Anisotropic Protein Patterned Microspheres”, 10th AIChE Annual Meeting. Salt Lake City, USA., 2010

Publisher : 10th AIChE Annual Meeting. Salt Lake City

Year : 2008

Biofriction at Lipid Modified Surfaces: Polymeric Gels

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Biofriction at Lipid Modified Surfaces: Polymeric Gels”, 8th World Biomaterials Congress (Poster). Amsterdam, Netherlands., 2008.

Publisher : 8th World Biomaterials Congress

Year : 2008

Incorporation of Globular Proteins into Lipid Monolayers after Conformational Change

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Incorporation of Globular Proteins into Lipid Monolayers after Conformational Change”, 8th World Biomaterials Congress (Poster). Amsterdam, Netherlands., 2008.

Publisher : 8th World Biomaterials Congress

Year : 2008

Bottom Up Synthesis Of Protein Like Nanoparticles With Enhanced Drug Loading And Their Post Synthetic Surface Modification

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Bottom Up Synthesis Of Protein Like Nanoparticles With Enhanced Drug Loading And Their Post Synthetic Surface Modification”, 8th World Biomaterials Congress (Oral). Amsterdam, Netherlands., 2008

Publisher : 8th World Biomaterials Congress

Year : 2008

Biofriction at Cell Mimetic Lipid Surfaces: Microspheres

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Biofriction at Cell Mimetic Lipid Surfaces: Microspheres”, 8th World Biomaterials Congress (Poster). Amsterdam, Netherlands., 2008.

Publisher : 8th World Biomaterials Congress

Year : 2008

Preliminary investigation on formation of embryoid bodies on cell mimetic surfaces and controlled ligand supplementation

Cite this Research Publication : Dr. Kaladhar Kamalasanan, Deb, D., and Sharma, C. P., “Preliminary investigation on formation of embryoid bodies on cell mimetic surfaces and controlled ligand supplementation”, 8th World Biomaterials Congress (Poster). Amsterdam, Netherlands., 2008.

Publisher : 8th World Biomaterials Congress

Year : 2008

Role of head group structure in regulating the packing density of lipid monolayers on phosphatidylcholines, and development of liposome delivering matrices for nerve conduit applications

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Role of head group structure in regulating the packing density of lipid monolayers on phosphatidylcholines, and development of liposome delivering matrices for nerve conduit applications”, 19th Annual meeting of the Materials Research Society of India (Poster) (Best Poster Award) . Thiruvananthapuram, Kerala, India., 2008.

Publisher : 19th Annual meeting of the Materials Research Society of India

Year : 2007

Calcification at micro domains: A bottom up approach for the synthesis of bioactive ceramic nanoparticles with high drug loading

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Calcification at micro domains: A bottom up approach for the synthesis of bioactive ceramic nanoparticles with high drug loading”, CMA 2007, Indo-US workshop on Ceramics for Medical Applications (Poster). IIT Madras, Chennai, TN, India., 2007.

Publisher : IIT Madras, Chennai, TN, India.

Year : 2007

Development of thin solid films of thermoresponsive nanoparticles and their characterization

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Development of thin solid films of thermoresponsive nanoparticles and their characterization”, BITE & RM (Poster). Thiruvananthapuram, Kerala, India., 2007.

Publisher : BITE & RM

Year : 2007

Screening of ligands for blood compatible applications by In silico methods: NSAID’s like Aspirin, Indomethacin & Diclofenac affinity for albumin

Cite this Research Publication : Dr. Kaladhar Kamalasanan, V., A. Rani, and Sharma, C. P., “Screening of ligands for blood compatible applications by In silico methods: NSAID’s like Aspirin, Indomethacin & Diclofenac affinity for albumin”, BITE & RM (Poster). Thiruvananthapuram, Kerala, India., 2007.

Publisher : BITE & RM

Year : 2007

Thermo Responsive Protein like Nanoparticles

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Thermo responsive protein like nanoparticles”, Society for Biomaterials, 31st Annual Meeting: A Multi Dimensional: Multi Disciplinary Approach to Biomaterials (Poster). Illinois, Chicago, USA., 2007.

Publisher : Society for Biomaterials

Year : 2007

Calcification at micro domains: Effect of insulin and ethanol

Cite this Research Publication :
Dr. Kaladhar Kamalasanan and Sharma, C. P., “Calcification at micro domains: Effect of insulin and ethanol”, Society for Biomaterials, 31st Annual meeting: A Multi Dimensional: Multi Disciplinary Approach to Biomaterials (Poster). Illinois, Chicago, USA., 2007.

Publisher : Society for Biomaterials

Year : 2006

Effect of Phosphatidylethanolamine in Fibroblast cell Adhesion and Proliferation

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Effect of phosphatidylethanolamine in fibroblast cell adhesion and proliferation”, Tissue Engineering and Regenerative Medicine International Society., Regenerate- World Congress on Tissue Engineering and Regenerative Medicine (Poster) (Travel Award). Westin Convention Center, Pittsburgh, Pennsylvania, USA, 2006.

Publisher : Westin Convention Center, Pittsburgh, Pennsylvania, USA

Year : 2006

Novel Albumin Self-Assembled Liposomes for Drug Delivery Applications

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Novel Albumin Self-Assembled Liposomes for Drug Delivery Applications”, Society for Biomaterials, Annual meeting: Biomaterials - The Enabling Technology (Poster) (Travel Award). Pittsburgh, Pennsylvania, USA., 2006.

Publisher : Society for Biomaterials

Year : 2005

Niomat- A Novel Solid Drug Delivery System to Deliver the Niosomes or Proniosomes with Drugs

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Niomat- A Novel Solid Drug Delivery System to Deliver the Niosomes or Proniosomes with Drugs”, Indo- Australian Conference on Biomaterials, Implantable Devices, Tissue Engineering and Regenerative Medicine (BITE & RM) (Poster). Thiruvananthapuram, Kerala, India, 2005

Publisher : BITE & RM

Year : 2005

A Novel Solid Liposome Based Drug Delivery System – Concept Proving Approach

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “A novel Solid Liposome Based Drug Delivery System - Concept Proving Approach”, Society for Biomaterials, 30th Anniversary meeting &Exposition, New Applications and Technologies (Poster). Memphis Cook Convention center, Memphis, USA., 2005.

Publisher : Society for Biomaterials, 30th Anniversary meeting &Exposition, New Applications and Technologies (Poster), Memphis Cook Convention center, Memphis, USA.

Year : 2004

Modification of chitosan using n-aryl anthranilic acid derivative for insulin delivery

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Modification of chitosan using n-aryl anthranilic acid derivative for insulin delivery”, Macro2004, International Conference on Polymers for Advanced Technologies, SPSI Annual General Body Meeting (Oral) (Best Oral Presentation). Thiruvananthapuram, India, 2004.

Publisher : Macro2004

Year : 2004

Modification of chitosan using N- aryl anthranilic acid derivative for blood compatible applications

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Modification of chitosan using N- aryl anthranilic acid derivative for blood compatible applications”, International Symposium on Advanced Materials and Processing (Oral) (Travel Award). IIT Kharagpur, India, 2004.

Publisher : IIT Kharagpur, India

Education & Work Experience

Specifics of Education and Work Experience in Academia, Research Institutes and Industry

  • Associate Professor (From April 1, 2021 to Present) at Amrita School of Pharmacy, Cochin, Kerala, India: Responsibilities briefly involves collaborating, mentoring, guiding, teaching students, developing research programs and developing technologies. Responsibilities (In detail); Teaching: M Pharm 1st sem; Controlled Drug Delivery Systems (CDDS) (7credits), Regulatory Affairs-  3credits, M Pharm 2nd Sem Molecular Pharmaceutics (Nano Tech and Targeted DDS) (7credits), Computer Aided Drug Delivery Systems (3Credits), B Pharm Pharmaceutical Regulatory Sciences (2Credits), Pharm D 4th Yr Biopharmaceutics and Pharmacokinetics (2Credits),   Research:  Guiding M Pharm student thesis- 12 completed, Research students (may leading to PhD) guiding-2, Research interns-3, Collaborations: International collaboration with Rochester Institute of Technology, NY, USA, Consulting for industries: Strategic consulting in technology development for companies in 3D printing, biomaterials and drug delivery systems, Societies: Executive board member, SBAOI and STERMI, Strategic planning, Organizing sessions and speeches, Reviewing for international conferences,  Consulting for clinical– COVID, cardiology, neurology, podology, endocrinology, cancer, Projects for extramural grants focus: COVID, Diabetes, Wound Healing, Bone regeneration, cardiovascular diseases, Administration: Board of studies committee, Research committee, Thrust Area Groups (Three), Anti-ragging squad, Assistant Warden ( Boys Hostel). 
  • Assistant Professor (From September 2015 to April 2021) at Amrita School of Pharmacy, Cochin, Kerala, India: Responsibilities briefly involves guiding, teaching students, developing research programs and developing technologies. Responsibilities (In detail); Teaching: M Pharm 1stsem; Controlled Drug Delivery Systems (CDDS)(5credits), Regulatory Affairs- 2credits, M Pharm 2nd Sem Molecular Pharmaceutics (Nano Tech and Targeted DDS)(5credits) Research:  Guiding M Pharm student thesis-10 completed, Research students (may leading to PhD) guiding-3, Consulting for industries: Strategic consulting in technology development for companies, Societies: Strategic planning, Organising sessions and speeches, Reviewing for international conferences,  Consulting for clinical– podeology, endocrinology, cancer, Projects for extramural grants focus: Diabetes, Wound Healing, Bone regeneration, Administration: Board of studies committee, Anti-ragging committee,  Research committee and IIIPC committee. 
  • Fellow Scientist-D (2012-2015; successfully completed – 3 years) at FADDS, BST Division, BMT Wing, SCTIMST Poojappura- Thiruvananthapuram, India, 695012, in prestigious Chitra High Value Fellowship (adhoc contract appointment against permanent vacancy), Responsibilities (Briefly): (1) Developing short term research programs in immunomodulation/ therapeutics and nano biotechnology, (2) Facility for advanced drug delivery systems (FADDS) second phase, Biosurface technology division in new research programs, (3) Lead author contributions in  TIFAC 2035 vision document on Biomaterials, (4) Commercially exploitable technologies evidenced in terms of technology briefing documents, (5) Patent submissions, (6) Publications, (6) International Research Programs (H2020), (7) International  Visists to Unviersity of Liverpool, Liverpool, UK. 
  • Postdoc in Immunomodulation and therapeutics as well as in the area of Nano biotechnology, Depts. of Chemical Engineering, bioengineering, immunology, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, USA,  Advisor: Dr. Steven R Little, (associate Professor) (2009 to 2012) (3-4 years).
  • Pre-postdoc Training in Immunology: Project based personal exchange program, DST-DAAD, Phillips University, Marburg, Germany, Advisor: Prof. Med. Harold Renz, (Director, BMFZ). (2006-08) (successfully completed visiting collaborative research for 2 years, 3months each for two times).
  • PhD in biomedical Engineering (Biosurface modification) Biosurface technology division, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Science and Technology, (An institute of national importance) Poojappura- Thiruvananthapuram, India, 695012, Mentor: Prof. Chandra Prakash Sharma (2003- 08). 
  • Junior Research Fellow in Oral delivery of insulin (nanotechnology for oral cavity delivery), NMITLI project, Biosurface technology division, Biomedical Technology Wing, SreeChitraTirunal Institute for Medical Science and Technology, (An Institute of National Importance) Poojappura- Thiruvananthapuram, India, 695012, (2001-2003) (2 years).
  • Master of Pharmacy (Industrial Pharmacy) (equivalent to pharmaceutics), at Annamalai University, Tamil Nadu, INDIA., Advisors: Subbal C Basak (Professor), and T. Subburaj (Vice President, Micro Labs Ltd) (1998-00).
  • Bachelor of Pharmacy at Dr. MGR Medical University, Tamil Nadu, INDIA (1993-97).
Research

Research Areas

Fundamental research areas: Material science (Biomaterials), Supramolecules, Biophysics, Cellular dynamics and Immunology, Drug delivery device design. With background in: Pharmaceutical sciences, Biomaterials and Nanotechnology. Applied research in: (2019) Personalised medicine, 3D printing, (1999) Drug delivery systems, Nanotechnology/Nanomedicine, Immunotherapeutics/Immunomodulation, Surface modification strategies, Tissue engineering and Regenerative medicine related to cancer, cardiology, COVID, periodontology (dental medicine), neurology, wound healing, hemorrhage and eye disease.

Grants

List of Projects Implemented/Written as a PI

  • 2019
    • Kaladhar K (PI) Self-assembling nanoparticulate insulin depots for delivering unaltered long-acting basal insulins by minimally invasive pen injections and microneedle technology (Submitted to DBT) (94.03Lakhs)
    • Kaladhar K (PI) Biomimetic nanoparticle-based antibiotic drug delivery for accelerated wound healing of surgical full-thickness chronic wounds, (Submitted to ICMR) (1.07Cr)
    • Kaladhar K (PI) Basal insulin delivery through nasal cavity using combustion derived carbon particle (CDCP) based biomimetic nanoparticles for treating diabetes mellitus (1.06Cr).
  • 2017
    • Kaladhar K (PI), Sabitha M, Biocompatible self-associating nanoparticulate insulin depot for reducing the number of injections per week to half in diabetic patients: structure-property-function study in diabetic rat model., DST nanomission project, (48.25Lakhs), (2017-2020) (Submitted to funding agency, DST-nanomission).
  • Before 2015
    • Kaladhar K (PI), RN Menon, VS Harikrishnan.,(2012) Supported and programmed CNS miniatures with a regenerative capacity to treat severe Spinal Cord Injury(SCI): Nanomedicine for glial scar therapeutics, OHF Project SCTIMST, (2.6Lakhs), 2013-2016, (implemented and report submitted).
    • Kaladhar K (PI), Renju R (Student), Peptide building blocks for nano-biomaterials in wound healing applications Seed grant, 30,000Rs, 2017-2018,(Grant approved), Amrita Viswa Vidyapeetham, Kochi, Kerala, India.

List of Projects Written as a Student/Tenured Track Faculty

  • Kaladhar K, Sharma CP, (2006) Center for advanced drug delivery systems (CADDS), DST, (42Crores) Asked to resubmit as subprojects.
  • Kaladhar K, Sharma CP, (2007) Facility for advanced drug delivery systems (FADDS), DST, (5Crores) (2008-2012).
  • Kaladhar K, Sharma CP, (2006), Evaluation of Pro and anti Th1/Th2 inflammatory profile of cells onto bio-material surface by studying the cytokine release profile, DST-DAAD project-based personal exchange program, (2006-2008).
  • Kaladhar K, CSIR Fellowship, (2006-2008).
  • Little SR, Balazs AC, NSF project (2010-2012).
  • Kaladhar K, Sharma CP (SCTIMST) and nine other international institutes, (2014), TB Vaccine, Horizon 2020.

Collaborations

  • Current: (2018-2020): Continuing all from last year with the inclusion of Megasis Biotek Ltd, Eranakulam, Kerala, Inda and entered an MOU with them on academic and research consultancy, (2017-2018) Institutional: (1) Nair SV Dean (Research) Sabitha M (Principal), Manita B Nair, Amrita Vishwa Vidyapeetham, Kochi, India., International (1) Tyagarajan B, Padmamalini T, University of Wyoming, Wyoming, USA., Industrial (1) R Narasimman, director, SKN Organics Pvt Ltd. (1) Dr. Praveen K, Amrita Hospital.
  • Past collaborations: Industrial (1) T Subburaj (Vice President) (Microlabs Ltd, Bangalore, 2000-2001), (2) Research (India): Chandra Prakash Sharma (Associate Head), SCTIMST, (2001 to present), (USA) Steven R Little (Chairman and Head) (2010-Present), AC Balazs (Chairman and Head), Bhaskar Goduku, Susheng Tan, Alexander Star, Riccardo Gottardi, Sam Rothenstein, Yanan Chen, Smitha Mathews, Siddharth Jhunjunwala, University of Pittsburgh, (2010 to present).

Product Developed/Consulted

  1. Aspirin based COVID medicine technology (developed and invited industries for technology transfer) (2021).
  2. BioGen Heart, Total artificial heart by 3D printing, VMHS, APMZ, AP, India (Consulted)(2020).
  3. Multi-Vitamin FDC tablet, Megasis Biotek Ltd, Eranakulam, Kerala, India, Preformulation optimization (Industrial project initiating) (2020).
  4. Multi-drug containing pediatric syrup (2018), SKAN  Research Labs Pvt Ltd, Puducherry, India, (Optimized the formuation and solved the incompatibility issues) (Product in market).
  5. Multi-drug containing eye lotion (2018),  SKAN  Research Labs Pvt Ltd, Puducherry, India,  Optimized the formulation and rectified the stability issues) (Product in market).
  6. Microdox DR Capsules USP, by Micro Labs Ltd, Bangalore, India (2001), (developed the formulation and scaled up), (Product in market) (Survived 7 years in market).

National Vision Road Map for Biomaterials

  • Kaladhar K, Sharma CP, Biomaterials vision document for TIFAC Vision-2035 roadmap on materials published in 2016.
Awards

Fellowships, Awards & Honors

2021-2024

  • Elected as Joint Secretary of Society for Tissue Engineering and Regenerative Medicine India for a period of three years (2021). 
  • Elected into the executive board of Society for Biomaterials and Artificial Organs India for a period of three years (2020).

2016-2020

  • Best poster award, International conference on advances in pharmaceutical and health sciences (ICAPHS-2020), NITTE, Mangaluru, Karnataka, India (2020).
  • Best poster award, 3rd international drug delivery congress-2019 (IDDC-2019), TN, Kerala, India (2019).
  • Co-chair in session entitled nanomaterials and infectious diseases, BioTERM 2019, International conference on Biomaterial based Therapeutic Engineering and Regenerative Medicine, (SBAOI ),  IIT Kanpur, India (2019).
  • Invited talk, In session: drug delivery and therapeutics, BioTERM 2019, International conference on Biomaterial based Therapeutic Engineering and Regenerative Medicine, (SBAOI), IIT Kanpur, India, (2019).
  • Peer Reviewer for 11th World Biomaterial Congress, Glasgow, Scotland, (2019).   
  • One of the ambassadors from India (total five) for 11th World Biomaterial Congress, Glasgow, Scotland, (2019).
  • Organising Committee member International Conference on Advances in Polymeric Materials and Human Healthcare, 16-18 Oct, 2019, International center Goa India, Organsied by Asian Polymer Association and STERMI, Goa, India, (2019).
  • Best poster award, Current trends in drug development and delivery technology, Chiral, nano and herbal technology, Nehru College of Pharmacy, Thrissur, Kerala, India, (2019).
  • Best poster award, Prime Pharma-conclave 2019 Prime college of pharmacy, Palakkad, Kerala, India, (2019). 
  • Organisingcommitte member, BioTerm 2019, International conference on Biomaterial based Therapeutic Engineering and Regenerative Medicine, IIT Kanpur, India, (2019).
  • Best poster award,  International conference in clinical pharmacy and pharmaceutical technology, JAMIA College of Pharmacy, Kerala, India, (2019).
  • Best poster award (Springer-nature), Biomet-2018, International conference on biomaterials, bioengineering and biotheranostics, VIT, Vellore, TN, India, (2018).
  • Coordinator, Research Industry Network (RIN) session at BioMet 2018, VIT, Vellore, India, (2018).
  • National Advisory Board member of BioMet 2018, VIT, Vellore, India, (2018).
  • National Advisory Board member of Asian Biomaterial Congress-6, 2017, Thiruvananthapuram, Kerala, India (2017). 

2012-2015

  • Author honoured, Biomaterials roadmap- Vision 2035, TIFAC, DST, India, Kolkotta, (2016).
  • Chitra High Value Fellowship (2012-2015) (2012).

1998-2012

  • Postdoctoral fellowship (2009-2012) (2009) 
  • Executive board member of Society for Tissue Engineering and Regenerative Medicine India (STERMI) (2008-2010) (2008). 
  • Best Poster Presentation Award, 19th MRSI-AGM, 19th AGM, Kerala, India (2008).
  • DST-DAAD Project Based Personal Exchange Program, Indo-German collaborative project (2006- 2008) (2006). 
  • Senior Research Fellowship (SRF) of Council of Scientific and Industrial Research (CSIR), India (2006-08) (2006).
  • Travel Grant from CSIR to attend Regenerate & Society for Biomaterials conferences at Pittsburgh, USA (2006). 
  • Best Oral Presentation Award in MACRO -2004, Society for Polymer Science, India (2004). 
  • General Aptitude Test for Engineering (GATE)(1998). 
Talks
  • Dr. Kaladhar Kamalasanan, (2016), (Author Briefing), Biomaterials chapter, 2035 Technology Vision, Technology Roadmap on materials, TIFAC, DST, India, IN national seminar on technology thrust on materials and manufacturing sector in India, CSIRCGCRI, Kolkutta, July 28-29 (Org by: CGCRI, IIM Kolkata, MIEEM, TIFAC).
  • Dr. Kaladhar Kamalasanan, (2016), (Invited Talk), Zero dimensional Single Walled Carbon Nanotubes and its application in super thin electronics and nanomedicine, BiTERM- 2016, InternationalConferrence on Biomaterials,Biodiagnostics,  Tissue Engineering, Drug Delivery and Regenerative Medicine, IIT Delhi, New Delhi, India, April 15-17, (Org by: Center for Biomedical Engineering, IIT Delhi,SBAOI, STERMI).
  • Dr. Kaladhar Kamalasanan, (2016) (Invited Speaker), The nanobridge in drug discovery and therapeutics: Nanomedicine, Advancing chemotherapy with a merge of medicinal chemistry and bioinformatics, Karpagam University, Karpagam College, June 17, (Org by: Karpagam University, AICTE).
  • Dr. Kaladhar Kamalasanan, (2016) (Invited Speaker), Traditional medicine to link with modern medicine:Research Possibilities, Medical Seminar, Kozhikode, Sept 17, (Org by: HKS, Kozhikode).
Student Guide
  • B Pharm (Thesis)
    • Student Details
      • Graduated: (2016-2017) (Published) Juna Joju (M Pharm, Amrita School of Pharmacy), Megha Hansen (M Pharm, Amrita School of Pharmacy), Alex Antony (studies abroad), Current: (2017-2018)(Published) Thomas Kuruvila (Symbiosis, MHA), Aiswari S Kumar (Joined for M Pharm, Amrita School of Pharmacy), Kavya SG (Joined for M Pharm, Amrita School of Pharmacy), Rasheed A(Joined for M Pharm, Amrita School of Pharmacy).
    • Thesis Details
      • (1) Juna J, Megha H, Alex A, (2017) Advanced bandages to stop haemorrhage from the lower limb extremities, (Guide Dr. Kaladhar K).
      • (2) Thomas K, Aiswari SK, Kavya SG, Abdul R, (2018) Early detection and therapy of epilepsy using point of care systems, (Guide Dr. Kaladhar K).
  • M. Pharm. (Thesis)
    • Graduated:
      • 2013-2014 (Published) Anupriya Mahesh (IF4.2) (Lecturer, Amrita School of Pharmacy, Kochi),
      • 2015- 2016 Jayakrishnapillai PV (IF4.2) (Aster, Dubai), Aravindsiva (IF7.7) (QC, Strides Arco lab, Bangalore),
      • 2016-2017 Rashmi Radhakrishnan (Scopus) (QA, Wockard Pharmaceuticals), Athira J Nair (Scopus) (Sun Pharma, Production, Hydrabad),
      • 2017-2018 Delma Decruz (Teaching, Vinayaka college pf pharmacy, Madurai, Tamilnadu, India), Jeevna (SKN, Madridge, FR&D, Bangalore), Juna Joju (Joined for pHD), Megha Hanssan (Joined for PhD).
    • Jayakrishnapillai PV, (2016) Insulin depots for therapeutic applications in diabetes mellitus, (Guide Dr. Kaladhar K) (IF 4.3).
    • Aravindsiva, Nanoemulsion for the treatment fo prostate cancer, (Co-guide: Kaladhar K, Guide: Sabitha M) (IF 7.8)
    • Rashmi R, Controlled local delivery of insulin for accelerated wound healing, (Guide Dr. Kaladhar K)
    • Athira J Nair, Developing a controlled insulin drug delivery system for bone regeneration applications, (Guide Dr. Kaladhar K).
    • Delma Decruz, Kajal based occular insert (Guide Dr. Kaladhar K)
    • Jeevna R, aspirin nanomedicine to extend the golden hour in stroke (Guide Dr. Kaladhar K)
    • Megha H Occular insert to deliver insulin (Guide Dr. Kaladhar K)
    • Juna J, Controlled delivery of antibiotic to wound bed (Guide Dr. Kaladhar K)
    • Aiswari S, (Guide Dr. Kaladhar K)
    • Shefrin, (Guide Dr. Kaladhar K)
  • Ph. D. (Thesis)
    • (2018-2019)
      • Juna Konikkara (Guide: Kaladhar K) ( currently enrolling)
      • Megha Hanssan (Guide: Kaladhar K) ( currently enrolling)
    • (2017-2018)
      • Renju Radhakrishnan (Guide: Kaladhar K) ( currently enrolling)
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