Publication Type : Patents
Publisher : U.S. Patent PCT/US2010/0517712009.
Source : U.S. Patent PCT/US2010/0517712009
Campus : Kochi
School : School of Pharmacy
Center : Amrita Institute of Medical Science
Verified : Yes
Year : 2009
Abstract : A method for making microparticles having an exterior surface that includes preparing a self-assembled arrangement of microparticles; contacting the self- assembled microparticles with a patch-forming agent resulting in a microparticle/patch-forming agent assembly having proximal regions between adjacent microparticles and/or proximal regions between a microparticle and another substrate, wherein the patch-forming agent is present in the proximal region; and condensing the patch- forming agent such that a pattern of a plurality of discrete patches of patch-forming agent are formed on the exterior surfaces of the microparticles at the proximal regions. A synthetic microsphere having an exterior spherical surface, wherein the exterior spherical surface comprises a first material and a plurality of discrete, uniformly-dimensioned, patches of a second bioactive material arranged in an orderly array over more than one hemisphere of the microsphere.
Cite this Research Publication : Dr. Kaladhar Kamalasanan and R. Steven, L., “Methods to prepare patchy microparticles”, U.S. Patent PCT/US2010/0517712009