Qualification: 
MPhil, MSc
jayalekshmih@am.amrita.edu

Jayalekshmi H. currently serves as Assistant Professor at the School of Biotechnology. She received her M. Phil. in Microbiology, Bharathidasan University, Tamil Nadu, 2007. She was also conferred M. Sc. Microbiology, Kasturba Medical College, Manipal University, Manipal in 1999.

Education

  • M.Phil(Microbiology)-Bharathidasan University, Tamil Nadu.
  • M Sc (Medical Microbiology), Kasturba Medical College, Manipal University, Karnataka B.Sc (Zoology), Kerala University, Kerala
  • B.Sc (Zoology), Kerala University, Kerala

Previous affiliations

  • Senior Lecturer (January 2014 - till date), Amrita School of Biotechnology, Amritapuri, Kerala.
  • Lecturer (October 2007- December 2014), Amrita School of Biotechnology, Amritapuri, Kerala
  • Senior Research fellow (2003- 2004) in CSIR funded project “Biochemical markers of alchoholic diseases”, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, Sikkim.
  • 4. Senior Research Fellow (2002 – 2003) in ICAR funded project ‘All India Net work Programme on Hemorrhagic Septicemia’ College of Veterinary and Animal Science, Kerala Agriculture University, Thrissur, Kerala.
  • 5. Microbiologist (2000 – 2002), Amrita Institute of Medical Sciences, Kochi,Kerala.

Teaching

Publications

Publication Type: Conference Proceedings

Year of Publication Publication Type Title

2013

Conference Proceedings

H. .Jayalekshmi, “Effect of Mangroves Extracts on Quorum Sensing and Biofilm Formation in S.aureus and P.aeruginosa.”, Amrita Bioquest. Kollam,Kerala, 2013.

Publication Type: Journal Article

Year of Publication Publication Type Title

2005

Journal Article

M. Maneesh, .Jayalekshmi, H., Dutta, S., Chakrabarti, A., and Dr. Damodaran Vasudevan, “Role of Oxidative Stress in Ethanol Induced Germ Cell Apoptosis—an Experimental Study in Rats”, Indian Journal of Clinical Biochemistry, vol. 20, pp. 62–67, 2005.[Abstract]


The study was undertaken to evaluate the possible involvement of oxidative stress in the pathogenesis of ethanol induced testicular atrophy in rats. Adult male rats were orally administered ethanol at a dose of 1.6 g/kg body weight/day for four weeks. Twenty-four hours after the last treatment the rats were sacrificed using anesthetic ether. Testes were removed and weighed. Apoptosis was studied by using the Feulgen reaction on 5 μ thin paraffin sections of testis. Testicular homogenate was prepared and centrifuged. The supernatant was used for the estimation of extent of lipid peroxidation and antioxidant defense status. There was significant reduction in body weight: and in testicular weight and diameter in ethanol treated rats. Extent of germ cell apoptosis was significantly high in ethanol treated rats. Ethanol treated rats showed significantly high tissue TBARS level and glutathione S-transferase activity; and low tissue ascorbic acid, reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase activities. Chronic ethanol administration resulted in high oxidative stress in the testes either due to increased extent of lipid peroxidation or due to decreased antioxidant defenses, and thereby induces germ cell apoptosis leading to testicular atrophy.

More »»

2005

Journal Article

M. Maneesh, .Jayalekshmi, H., Dutta, S., Chakrabarti, A., and Dr. Damodaran Vasudevan, “Effect of Chronic Ethanol Administration on Testicular Antioxidant System and Steroidogenic Enzyme Activity in Ratsc”, Indian J Exp Biol, vol. 43, pp. 445–449, 2005.[Abstract]


In order to find out the effect of chronic ethanol administration on testicular antioxidant system and steroidogenic enzyme activity, male rats fed with ethanol 1.6g/kg body weight per day for four weeks were studied. Besides a drastic reduction in body and testis weight, there was decrease in ascorbic acid, reduced glutathione and activities of superoxide dismutase, catalase, glutathione reductase and glutathione peroxidase in the testicular tissue of the treated animals. Simultaneously, there was increase in lipid peroxidation and glutathione S-transferase activity. Activities of 3β-hydroxy steroid dehydrogenase and 17β-hydroxy steroid dehydrogenase were also found decreased in the treated animals. The results indicate that chronic ethanol administration resulted in increase in oxidative stress and decrease in the activities of steroidogenic enzymes in the rat testes. More »»

Participation In Conference And Workshop

i plant workshop,Amrita School of Biotechnology,Amritapuri,Kollam,Kerala. August 2014
Workshop on Introduction to research methodology-conducted by IIT Bombay -Amrita School of Engineering,Amritapuri,Kerala June 2012
Workshop on Basic Concepts in Modern Biology ,Amrita School of Biotechnology,Amritapuri,Kerala December 2006
Training workshop on AIDS,Kasturba Medical College,Manipal,Manipal University,Karnataka December 1998
XXII National congress of Indian association of Medical Microbiologists.Kasturba Medical College,Manipal,Manipal University,Karnataka. November 1998
Workshop on Rapid diagnostic techniques in Clinical microbiology with special emphasis to HIV and Tuberculosis,Kasturba Medical College,Manipal,Manipal University,Karnataka. November 1998
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