Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Indian journal of experimental biology
Source : Indian journal of experimental biology, National Institute of Science Communication and Information Resources, Volume 47, Number 7, p.608–610 (2009)
Campus : Amritapuri
School : School of Biotechnology
Department : Microbiology
Year : 2009
Abstract : Ethanol intoxication resulted in high extent of lipid peroxidation, and reduction in antioxidant defenses (decreased GSH, GSH/GSSG ratio, and catalase, SOD and GPx activities) and (Na+/K+)-ATPase activity in kidney. Alpha-tocopherol treatment effectively protected kidney from ethanol induced oxidative challenge and improved renal (Na+/K+)-ATPase activity. Ethanol induced oxidative stress in the kidney and decreased (Na+/K+)-ATPase activity could be reversed by treatment with ascorbic acid.
Cite this Research Publication : M. Mailankot, Jayalekshmi H., Chakrabarti, A., Alang, N., and Vasudevan, D. M., “Effect of Alpha-Tocopherol Supplementation on Renal Oxidative Stress and Na+/K+-Adenosine Triphosphatase in Ethanol Treated Wistar Rats.”, Indian journal of experimental biology, vol. 47, pp. 608–610, 2009.