Course

Unit 1

Genes, chromosomes & heridity: Introduction, DNA as genetic material

– Cellular Reproduction – Mendelism: Basic Principles

Unit 2

Extension and variation of mendelism: Chromosomal Basis – Variation in chromosome

number & structure 

Unit 3

Linkage and crossing over: Linkage, Crossing Over and Chromosome Mapping –

Genetics of Bacteria and their viruses- Extra Nuclear Inheritance.

Unit 4

DNA, gene expression & genomics:   Molecular structure of DNA – Mutation, DNA repair & Recombination ––Transposable elements 

Unit 5

Gene regulation and expression:   Regulation of gene expression – Cancer & Regulation of Cell Cycle

LEARNING OBJECTIVES:

Genetics is the study of heredity and genes. The aim of this course is to strengthen the

Mendelian principles along with other molecular genetics topics like recombination, pedigree

analysis, transposons. This course will help students to venture in to the different areas of

biomedical sciences.

COURSE OUTCOMES:

After completing the course, students shall be able to

CO1. To understand the basic concept of Mendelian principles and learn its application in different genetic experiments. This would help the students to solve the majority of the

genetic problems.

CO2. To extrapolate the deviations from the standard mendelian laws in few cases and

learning the mechanisms.

REFERENCES:

1. Genetics – 6th Edition – Snustad & Simmons – Wiley, 2011.
2. Concepts of Genetics – 10th Edition – Klug et al – Pearson, 2020