Course

SYLLABUS:

Unit 1: Importance of bacterial pathogenesis, host immunity, antibacteirals and prophylactics: Bacteria and disease.

Unit 2:Host pathogen interaction. Importance of the study of bacterial pathogenesis. First line of host defense, innate immunity, antibodies and T cells. Normal Microbiota. Bacterial strategies to overcome host defense.

Unit 3: Molecular biology of virulence. Prophlactics and antibacterials.

Unit 4: Background Information of Viral Pathogenesis: Representative Organisms :DNA Virus replication strategies, RNA virus replication strategies.

Unit 5:Influenza virus and Para influenza viruses. SARS and respiratory viruses. Measles, mumps and rubella viruses. Herpes virus. Enteroviruses. Pox viruses. Retroviruses, HIV and retroviral therapy. Oncogenic viruses. Hepatitis viruses.

LEARNING OBJECTIVES: 

The course introduces the basic concepts and molecular aspects of Bacterial and Viral Pathogenesis. Helps students to extrapolate those concepts in explaning the pathogenesis and pathology of different bacterial and viral pathogens.

COURSE OUTCOMES:

After completing the course, students shall be able to

6. To understand the pathogenesis from the perspective of the etiological agents.

7. Bacterial and viral virulence factors.

8. The host responses to bacterial and viral infections.

9. Discussions on specific bacterial and viral pathogens.

10. Discussion of emerging diseases

REFERENCES:

1. Virology, Flint.
2. Microbiology, Ananthanarayanan, Panicker.
3. Virology, James jay.
4. Bacterial Pathogenesis: A Molecular Approach (Paperback) by A. A. Salyers and D. D. Whitt.
5. Principles of Bacterial Pathogenesis by Eduardo A. Groisman.