| Course Name | Nanomedicine: Diagnosis & Therapy |
| Course Code | 25NBT511 |
| Program | M. Sc. Nanobiotechnology (NBT) |
| Semester | 2 |
| Credits | 3 |
| Campus | Kochi |
Concepts of Nanomedicine – Controlled drug delivery, Advantages of nanotechnology in drug delivery, Design, fabrication, evaluation and applications of the nanosystems for drug and gene delivery – Polymeric Nanoparticles, Liposomes, Micelles, Solid Lipid Nanoparticles, Dendrimers, Implants and inserts, General characteristics of nanomaterials used in drug/gene delivery – Drug encapsulation, Drug release, Effect of particle size/surface charge in drug delivery
Nano Drug Delivery via Different Routes: Oral Drug Delivery – Concepts of Mucoadhesion; Intravenous Drug Delivery using nanoparticles – Concept of opsonisation; Transdermal, Intranasal and Ocular Drug Delivery using Nanoparticles, Strategies for Advanced Drug Delivery:-Prodrug and Bioconjugation; Concept of Drug Targeting, Site Specific Drug delivery utilizing Monoclonal Antibodies, Peptides and other biomolecules, Nanovaccines
Medical Diagnosis– from biomarkers to cells and tissues; Clinical diagnostic imaging tools: MRI, PET, CT, Ultrasound, Nuclear and Optical imaging –an overview; Diagnostic nanoscale materials in imaging; Molecular imaging techniques
Nanobiosensors in diagnosis– electrochemical sensors, enzymatic and non-enzymatic sensors, cantilever based sensors, piezoelectric biosensors, Lab-on-a-chip concept, Microfluidics, surface enhanced Raman spectroscopy based diagnostics, surface plasmon based biosensors; Current nanotechnology based diagnostics in use and under clinical trials.
Pre-requisites: Basic level physics, chemistry and biology
Total number of classes: 45
COURSE OUTCOMES:
Upon successful completion, students will have the knowledge and skills to:
COURSE OUTCOMES:
CO 1 – Understand the fundamental concepts of nanomedicine and the benefits of nanodrug delivery
CO 2 – Provide an overview of various types of advanced delivery systems based on nanotechnology for delivering drugs, biomolecules, genes, vaccines
CO 3 – Introduce the concepts of targeted drug delivery
CO 4 – An overview of the diverse medical diagnostic tools and the relevance of nanomaterials in medical diagnostics
CO 5 – Fundamentals of biosensing and the importance of nanotechnology in biosensing
CO 6 – Understanding about various nano bio-sensors and microfluidic sensors and the current status of nanotechnology based diagnostic devices commercially available
PROGRAM OUTCOME:
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
MAPPING (CO/PO)
0 – No affinity; 1 – low affinity; 2 – Medium affinity; 3 – High affinity
CO–PO Mapping:
|
COs |
PO1 |
PO2 |
PO3 |
PO4 |
PO5 |
PO6 |
PO7 |
PO8 |
PO9 |
PO10 |
PO11 |
PO12 |
|
CO1 |
2 |
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
|
CO2 |
3 |
2 |
2 |
2 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
|
CO3 |
2 |
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
|
CO4 |
3 |
2 |
2 |
2 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
|
CO5 |
3 |
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
|
CO6 |
3 |
2 |
2 |
3 |
3 |
3 |
1 |
1 |
1 |
0 |
0 |
2 |
PROGRAM SPECIFIC OUTCOMES (PSO):
PSO1: Mastery of Nanomaterial Science and Characterization
PSO2: Understanding of Cellular and Molecular Systems
PSO3: Application of Nanobiotech in Diagnostics and Therapy
PSO4: Experimental Design and Data Analysis
PSO5: Research Competency and Methodological Rigor
PSO6: Industry and Career Readiness
CO–PSO Mapping
|
COs |
PSO1 |
PSO2 |
PSO3 |
PSO4 |
PSO5 |
PSO6 |
|
CO1 |
3 |
2 |
3 |
3 |
2 |
3 |
|
CO2 |
3 |
3 |
3 |
2 |
2 |
3 |
|
CO3 |
3 |
3 |
3 |
3 |
3 |
3 |
|
CO4 |
3 |
3 |
3 |
3 |
3 |
3 |
|
CO5 |
3 |
3 |
3 |
3 |
3 |
3 |
|
CO6 |
3 |
3 |
3 |
3 |
3 |
3 |
TEXT BOOKS/ REFERENCES:
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