| Course Name | Organ System Physiology |
| Course Code | 25SCR533 |
| Program | M. Sc. Stem Cell Technology and Regenerative Medicine |
| Semester | 1 |
| Credits | 3 |
| Campus | Kochi |
(Lectures 5)
Introduction, body water and distribution, regulation of water within extracellular, transcellular, and intracellular compartments, determination of compartmental fluid volumes, electrolyte distribution and their role in cell membrane potential
(Lectures 4)
Blood the tissue and its components, serum, plasma, the coagulation process and dyscrasias, advancement in blood substitutes and their principle, and the lymphatic system
(Lectures 6)
Cardiovascular system and the vascular tree, cardiac electrophysiology, arrythmias, pressure and volume changes in the ventricular chambers, cardiac cycle, valve kinetics, cardiac muscle physiology and calcium regulation, and cardiac biomedical technology
(Lectures 4)
Pulmonary system, mechanics of ventilation, bronchial and alveolar cell functions geared to exchange gases, pulmonary function tests and assisted respiration technology
(Lectures 6)
Hepatobiliary system, pancreas and the gut, hepatocyte architecture and function, blood-bile dynamics, pancreatic acini function, advancement in artificial liver and pancreas development, and gut physiology
(Lectures 5)
Renal physiology, function of nephron, process of urine formation, pressures across the Bowmans membrane, and developments in body fluid dialysis
(Lectures 10)
Nerve function, introductory neurophysiology, synapse physiology, neural circuits, signal processing in the special sense organs, cognition, and brain machine interface
(Lectures 5)
Reproductive and endocrine system, hormonal axis, and regulation in various endocrine glands
Pre-requisites: Undergraduate level basic biology
Total number of classes: 45
Preamble: This course builds on basic physiology and delves into individual organ systems and its cellular make up, their design, structure, and function. Each organ system will be discussed from a perspective of its function and how tissue and cellular hierarchies, in terms of their architecture and processes, contribute to organ system homeostasis. Current progress in terms of biomedical advancement in each organ system will also be explored.
Course Outcomes
CO1. Describe the structure and function of major human organ systems and their role in maintaining homeostasis.
CO2. Explain how fluid and electrolyte balance influences cellular and systemic physiology.
CO3. Discuss key physiological processes in the cardiovascular, pulmonary, renal, and gastrointestinal systems.
CO4. Identify biomedical technologies and therapies used to support or replace organ function.
CO5. Summarize neurophysiological, endocrine, and reproductive functions, including brain-machine interface applications.
Programme Outcomes (PO)
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
|
PO1 |
PO2 |
PO3 |
PO4 |
PO5 |
PO6 |
PO7 |
PO8 |
PO9 |
PO10 |
PO11 |
PO12 |
|
|
CO1 |
3 |
1 |
1 |
– |
1 |
– |
– |
– |
3 |
2 |
– |
1 |
|
CO2 |
3 |
3 |
1 |
– |
1 |
– |
– |
– |
3 |
2 |
– |
1 |
|
CO3 |
3 |
3 |
3 |
– |
1 |
– |
– |
– |
3 |
2 |
– |
1 |
|
CO4 |
3 |
2 |
1 |
– |
1 |
– |
– |
– |
3 |
2 |
– |
1 |
|
CO5 |
2 |
1 |
3 |
2 |
1 |
3 |
– |
2 |
3 |
2 |
– |
1 |
Program Specific Outcomes. (PSO)
PSO1. Demonstrate comprehensive knowledge of stem cell biology and their clinical and research relevance.
PSO2. Apply core laboratory techniques for stem cell isolation, characterization, and manipulation.
PSO3. Integrate principles of tissue engineering and biomaterials for regenerative applications.
PSO4. Analyze drug delivery, pharmacokinetics, and bioinformatics relevant to stem cell-based therapies.
PSO5. Evaluate ethical, regulatory, and translational aspects of stem cell product development.
PSO6. Bridge basic science with translational approaches in regenerative medicine and gene therapy.
PSO7. Design and interpret experimental strategies for stem cell-based disease
modeling and preclinical studies.
|
– |
PSO1 |
PSO2 |
PSO3 |
PSO4 |
PSO5 |
PSO6 |
PSO7 |
|
C O |
|||||||
|
CO 1 |
2 |
1 |
2 |
2 |
– |
2 |
2 |
|
CO 2 |
2 |
1 |
1 |
– |
– |
2 |
1 |
|
CO 3 |
2 |
– |
1 |
2 |
2 |
1 |
|
|
CO 4 |
2 |
– |
3 |
– |
2 |
3 |
2 |
|
CO 5 |
2 |
– |
2 |
– |
– |
2 |
1 |
Evaluation Pattern: 50+50 = 100
|
Internal Assessment – 50% |
||
|
Periodical 1 |
Exam |
20% |
|
Periodical 2 |
Exam |
20% |
|
Continuous Assessment |
Assignment/Test/Quiz |
10% |
|
50% |
||
|
End Semester Examination- 50% |
||
|
Theory Exam |
50% |
|
|
50% |
||
|
Total |
100% |
|
Textbook
John E. Hall, “Guyton and Hall Textbook of Medical Physiology”, 13e Elsevier, 2015
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