Course

1.Separation of Binary MixturesIncludes separation, preliminary investigations, determinations of saturation/unsaturation, detection of elements by Lassaignes test, functional group identification, derivative preparation, determination of melting points of the derivatives and calculation of Rf values from TLCThe following mixtures can be given:(a)Acid and hydrocarbon(b)Phenol and aldehyde(c)Phenol and acid(d)Phenol and amine(e)Acid and ester(f)Halo compound and aldehyde(g)Acid and aldehyde(h)Amine and aldehyde(i)Amine and ketone(j)Alcohol and hydrocarbon2.Thin layer chromatography to determine Rf values of compounds(a)2-nitroaniline(b)4-nitroaniline(c)Cinnamic acid and 2-nitroaniline(d)Acetophenone(e)Ethyl benzoate3.Simple column chromatography to separate the components of binary mixtures(a)Hydrocarbon and ester(b)Aldehyde and amine

REFERENCES1.P.W.G. Smith, A.J. Hannaford, B.S. Furnis and A.R. Tatchell, Vogels Textbook of Practical Organic Chemistry, ELBS/Longman, 1989.2.Ralph L. Shriner, Christine K.F. Hermann, Terence C. Morrill, David Y. Curtin, Reynold C. Fuson, Systematic Identification of Organic Compounds, John Wiley & Sons, 2003.3.Mann and Saunders, Practical Organic Chemistry, Pearson edition, 2009.