Unit I (10 Hours)
Basic principles of Cell injury and Adaptation: Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellu- lar injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes
(Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance
Basic mechanism involved in the process of inflammation and repair: Introduction, Clinical signs of inflammation, Different types of Inflammation, Mechanism of In- flammation – Alteration in vascular permeability and blood flow, migration of WBC’s,Mediators of inflammation,Basic principles of wound healing in the skin,Pathophysiology of Atherosclerosis
Unit II (10 Hours)
Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, athero- sclerosis and arteriosclerosis)
Respiratory system: Asthma, Chronic obstructive airways diseases.
Renal system: Acute and chronic renal failure.
Unit III (10 Hours)
Haematological Diseases: Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, heredi- tary acquired anemia, hemophilia
Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones
Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophre- nia and Alzheimer’s disease.
Gastrointestinal system: Peptic Ulcer
Unit IV (08 Hours)
- Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease.
- Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout
- Principles of cancer: classification, etiology and pathogenesis of cancer
Unit V (07 Hours)
Infectious diseases: Meningitis,Typhoid, Leprosy, Tuberculosis
Urinary tract infections
Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea